T-Cell Surface Glycoprotein CD3 Gamma (CD3g)

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T3G; CD3-G; CD3g Molecule,Gamma(CD3-TCR Complex); CD3-GAMMA

T-Cell Surface Glycoprotein CD3 Gamma (CD3g)
CD3G (gamma chain) is one of the four peptides (gamma, delta, epsilon and zeta) that form CD3. Defects in CD3G are associated with T cell immunodeficiency.
T-Cell Surface Glycoprotein CD3 Gamma is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD118Hu01 Recombinant T-Cell Surface Glycoprotein CD3 Gamma (CD3g) Positive Control; Immunogen; SDS-PAGE; WB.
RPD118Hu02 Recombinant T-Cell Surface Glycoprotein CD3 Gamma (CD3g) Positive Control; Immunogen; SDS-PAGE; WB.
RPD118Hu03 Recombinant T-Cell Surface Glycoprotein CD3 Gamma (CD3g) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAD118Hu23 Monoclonal Antibody to T-Cell Surface Glycoprotein CD3 Gamma (CD3g) WB; IHC; ICC; IP.
MAD118Hu21 Monoclonal Antibody to T-Cell Surface Glycoprotein CD3 Gamma (CD3g) WB
MAD118Hu24 Monoclonal Antibody to T-Cell Surface Glycoprotein CD3 Gamma (CD3g) WB
MAD118Hu22 Monoclonal Antibody to T-Cell Surface Glycoprotein CD3 Gamma (CD3g) WB; IHC; ICC; IP.
MAD118Hu25 Monoclonal Antibody to T-Cell Surface Glycoprotein CD3 Gamma (CD3g) WB; IHC; ICC; IP.
MAD118Hu26 Monoclonal Antibody to T-Cell Surface Glycoprotein CD3 Gamma (CD3g) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for T-Cell Surface Glycoprotein CD3 Gamma (CD3g) CLIA Kit Customized Service Offer
n/a ELISA Kit for T-Cell Surface Glycoprotein CD3 Gamma (CD3g) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant T-Cell Surface Glycoprotein CD3 Gamma (CD3g) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to T-Cell Surface Glycoprotein CD3 Gamma (CD3g) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to T-Cell Surface Glycoprotein CD3 Gamma (CD3g) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for T-Cell Surface Glycoprotein CD3 Gamma (CD3g) CLIA Kit Customized Service Offer
n/a ELISA Kit for T-Cell Surface Glycoprotein CD3 Gamma (CD3g) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant T-Cell Surface Glycoprotein CD3 Gamma (CD3g) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to T-Cell Surface Glycoprotein CD3 Gamma (CD3g) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to T-Cell Surface Glycoprotein CD3 Gamma (CD3g) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for T-Cell Surface Glycoprotein CD3 Gamma (CD3g) CLIA Kit Customized Service Offer
n/a ELISA Kit for T-Cell Surface Glycoprotein CD3 Gamma (CD3g) ELISA Kit Customized Service Offer
  1. "Primary structure of the T3 gamma subunit of the T3/T cell antigen receptor complex deduced from cDNA sequences: evolution of the T3 gamma and delta subunits."EMBO J. 5:1799-1808(1986) [PubMed] [Europe PMC] [Abstract]
  2. "Physical linkage of three CD3 genes on human chromosome 11."EMBO J. 6:2953-2957(1987) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
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  6. "A novel di-leucine motif and a tyrosine-based motif independently mediate lysosomal targeting and endocytosis of CD3 chains."Cell 69:1143-1157(1992) [PubMed] [Europe PMC] [Abstract]
  7. "Brief report: primary immunodeficiency caused by mutations in the gene encoding the CD3-gamma subunit of the T-lymphocyte receptor."N. Engl. J. Med. 327:529-533(1992) [PubMed] [Europe PMC] [Abstract]
  8. "Differential biological role of CD3 chains revealed by human immunodeficiencies."J. Immunol. 178:2556-2564(2007) [PubMed] [Europe PMC] [Abstract]
  9. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  10. "Crystal structure of the human T cell receptor CD3 epsilon gamma heterodimer complexed to the therapeutic mAb OKT3."Proc. Natl. Acad. Sci. U.S.A. 101:7675-7680(2004) [PubMed] [Europe PMC] [Abstract]