Glycoprotein M6B (GPM6B)

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M6b; Neuronal membrane glycoprotein M6-b

Glycoprotein M6B (GPM6B)
GPM6B encodes a membrane glycoprotein that belongs to the proteolipid protein family. Proteolipid protein family members are expressed in most brain regions and are thought to be involved in cellular housekeeping functions, such as membrane trafficking and cell-to-cell communication.
The cDNAs, designated M6a and M6b, are highly similar to the myelin proteolipid protein and are expressed during early development of the mouse central nervous system. M6b is expressed in both neurons and glia and was detected in the cerebellar Bergmann glia, in glia within white matter tracts of the cerebellum and cerebrum, and in embryonic dorsal root ganglia Olinsky et al. (1996) mapped the gene to Xp22.2 by fluorescence in situ hybridization.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Glycoprotein M6B (GPM6B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Glycoprotein M6B (GPM6B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Glycoprotein M6B (GPM6B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Glycoprotein M6B (GPM6B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glycoprotein M6B (GPM6B) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Glycoprotein M6B (GPM6B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Glycoprotein M6B (GPM6B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Glycoprotein M6B (GPM6B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Glycoprotein M6B (GPM6B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glycoprotein M6B (GPM6B) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Glycoprotein M6B (GPM6B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Glycoprotein M6B (GPM6B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Glycoprotein M6B (GPM6B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Glycoprotein M6B (GPM6B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glycoprotein M6B (GPM6B) ELISA Kit Customized Service Offer
  1. "Chromosomal mapping of the human M6 genes."Genomics 33:532-536(1996) [PubMed] [Europe PMC] [Abstract]
  2. "Mutation analysis of the M6b gene in patients with Rett syndrome."Am. J. Med. Genet. 78:165-168(1998) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Membrane glycoprotein M6B interacts with the human serotonin transporter."J. Mol. Neurosci. 37:191-200(2009) [PubMed] [Europe PMC] [Abstract]
  7. "GPM6B regulates osteoblast function and induction of mineralization by controlling cytoskeleton and matrix vesicle release."J. Bone Miner. Res. 26:2045-2051(2011) [PubMed] [Europe PMC] [Abstract]
  8. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]