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Acid Phosphatase 2, Lysosomal (ACP2)

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Lysosomal Acid Phosphatase

Acid Phosphatase 2, Lysosomal (ACP2)
CCC D089
HGNC 123
MGI 87882
PubMed 2835668
RGD 2021
UniProt P11117
Wiki ACP2
Lysosomal acid phosphatase is composed of two subunits, alpha and beta, and is chemically and genetically distinct from red cell acid phosphatase. Lysosomal acid phosphatase 2 is a member of a family of distinct isoenzymes which hydrolyze orthophosphoric monoesters to alcohol and phosphate.
ACP2 is the beta subunit of lysosomal acid phosphatase (LAP). LAP is chemically and genetically distinct from red cell acid phosphatase. The encoded protein belongs to a family of distinct isoenzymes which hydrolyze orthophosphoric monoesters to alcohol and phosphate. Mutations in this gene or in the related alpha subunit gene cause acid phosphatase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD089Hu01 Recombinant Acid Phosphatase 2, Lysosomal (ACP2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD089Hu01 Polyclonal Antibody to Acid Phosphatase 2, Lysosomal (ACP2) WB
MAD089Hu21 Monoclonal Antibody to Acid Phosphatase 2, Lysosomal (ACP2) WB; IHC; ICC; IP.
Assay Kits SED089Hu ELISA Kit for Acid Phosphatase 2, Lysosomal (ACP2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD089Mu01 Recombinant Acid Phosphatase 2, Lysosomal (ACP2) Positive Control; Immunogen; SDS-PAGE; WB.
RPD089Mu02 Recombinant Acid Phosphatase 2, Lysosomal (ACP2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD089Mu01 Polyclonal Antibody to Acid Phosphatase 2, Lysosomal (ACP2) WB; IHC; ICC; IP.
PAD089Mu02 Polyclonal Antibody to Acid Phosphatase 2, Lysosomal (ACP2) WB; IHC; ICC; IP.
Assay Kits SED089Mu ELISA Kit for Acid Phosphatase 2, Lysosomal (ACP2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Acid Phosphatase 2, Lysosomal (ACP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Acid Phosphatase 2, Lysosomal (ACP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Acid Phosphatase 2, Lysosomal (ACP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Acid Phosphatase 2, Lysosomal (ACP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Acid Phosphatase 2, Lysosomal (ACP2) ELISA Kit Customized Service Offer
  1. "Human lysosomal acid phosphatase: cloning, expression and chromosomal assignment."EMBO J. 7:2343-2350(1988) [PubMed] [Europe PMC] [Abstract]
  2. "Structure of the human lysosomal acid phosphatase gene."Eur. J. Biochem. 183:611-616(1989) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Human chromosome 11 DNA sequence and analysis including novel gene identification." Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Sequential processing of lysosomal acid phosphatase by a cytoplasmic thiol proteinase and a lysosomal aspartyl proteinase."EMBO J. 8:3215-3219(1989) [PubMed] [Europe PMC] [Abstract]
  7. "Deficiency of lysosomal acid phosphatase. A new familial metabolic disorder."N. Engl. J. Med. 282:302-307(1970) [PubMed] [Europe PMC] [Abstract]
  8. "Human lysosomal acid phosphatase is transported as a transmembrane protein to lysosomes in transfected baby hamster kidney cells."EMBO J. 7:2351-2358(1988) [PubMed] [Europe PMC] [Abstract]
  9. "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
  10. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]