Carbonic Anhydrase XI (CA11)
[Edit]CA-XI; CAXI; CA-RP XI; CARP2; CA-RP XI; Carbonic Anhydrase-Related Protein XI; Carbonic Anhydrase-Related Protein 2
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Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid.
CA XI is likely a secreted protein, however, radical changes at active site residues completely conserved in CA isozymes with catalytic activity, make it unlikely that it has carbonic anhydrase activity. It shares properties in common with two other acatalytic CA isoforms, CA VIII and CA X. CA XI is most abundantly expressed in brain, and may play a general role in the central nervous system.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Carbonic Anhydrase XI (CA11) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Carbonic Anhydrase XI (CA11) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Carbonic Anhydrase XI (CA11) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Carbonic Anhydrase XI (CA11) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Carbonic Anhydrase XI (CA11) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Carbonic Anhydrase XI (CA11) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Carbonic Anhydrase XI (CA11) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Carbonic Anhydrase XI (CA11) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Carbonic Anhydrase XI (CA11) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Carbonic Anhydrase XI (CA11) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Carbonic Anhydrase XI (CA11) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Carbonic Anhydrase XI (CA11) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Carbonic Anhydrase XI (CA11) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Carbonic Anhydrase XI (CA11) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Carbonic Anhydrase XI (CA11) | ELISA Kit Customized Service Offer |
- "Sequence and tissue expression of a novel human carbonic anhydrase-related protein, CARP-2, mapping to chromosome 19q13.3."Biochem. Biophys. Res. Commun. 253:364-367(1998) [PubMed] [Europe PMC] [Abstract]
- "cDNA sequence, mRNA expression, and chromosomal localization of human carbonic anhydrase-related protein, CA-RP XI."Biochim. Biophys. Acta 1431:518-524(1999) [PubMed] [Europe PMC] [Abstract]
- "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Evolutionarily conserved, 'acatalytic' carbonic anhydrase-related protein XI contains a sequence motif present in the neuropeptide sauvagine: the human CA-RP XI gene (CA11) is embedded between the secretor gene cluster and the DBP gene at 19q13.3."Genomics 54:484-493(1998) [PubMed] [Europe PMC] [Abstract]
- "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."J. Proteome Res. 4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]