Amyloid Beta Precursor Protein Binding Protein B3 (APBB3)
[Edit]APB-B3; SRA; FE65L2; FE65-L2; Fe65L2 isoform 484; Alzheimer's beta-amyloid interaction protein; Amyloid beta (A4) protein-binding, family B, member 3, isoform CRA_g
Amyloid beta A4 precursor protein-binding family B member 3 is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP. Multiple transcript variants encoding several different isoforms have been found for this gene.
Like Fe65 and Fe65L1, the rat Fe65L2 protein contains 2 phosphotyrosine-binding (PTB) domains and a WW domain. Northern blot analysis detected predominant expression of a 2-kb Fe65L2 mRNA in rat brain and testis.Fe65L2 encodes a deduced 486-amino acid protein that shares 86% sequence identity with the rat protein.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Amyloid Beta Precursor Protein Binding Protein B3 (APBB3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Amyloid Beta Precursor Protein Binding Protein B3 (APBB3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Amyloid Beta Precursor Protein Binding Protein B3 (APBB3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Amyloid Beta Precursor Protein Binding Protein B3 (APBB3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Amyloid Beta Precursor Protein Binding Protein B3 (APBB3) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Amyloid Beta Precursor Protein Binding Protein B3 (APBB3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Amyloid Beta Precursor Protein Binding Protein B3 (APBB3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Amyloid Beta Precursor Protein Binding Protein B3 (APBB3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Amyloid Beta Precursor Protein Binding Protein B3 (APBB3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Amyloid Beta Precursor Protein Binding Protein B3 (APBB3) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPC959Ra01 | Recombinant Amyloid Beta Precursor Protein Binding Protein B3 (APBB3) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAC959Ra01 | Polyclonal Antibody to Amyloid Beta Precursor Protein Binding Protein B3 (APBB3) | WB; IHC; ICC; IP. |
MAC959Ra21 | Monoclonal Antibody to Amyloid Beta Precursor Protein Binding Protein B3 (APBB3) | WB; IHC; ICC; IP. | |
Assay Kits | SEC959Ra | ELISA Kit for Amyloid Beta Precursor Protein Binding Protein B3 (APBB3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
- "Molecular cloning of human Fe65L2 and its interaction with the Alzheimer's beta-amyloid precursor protein."Neurosci. Lett. 261:143-146(1999) [PubMed] [Europe PMC] [Abstract]
- "The sequence of the human genome." Science 291:1304-1351(2001) [PubMed] [Europe PMC] [Abstract]