≡

Amyloid Beta Precursor Protein Binding Protein 2 (APPBP2)

[Edit]

PAT1; Protein Interacting With APP Tail 1,Cytoplasmic Tail; Amyloid protein-binding protein 2; Protein interacting with APP tail 1

Amyloid Beta Precursor Protein Binding Protein 2 (APPBP2)
CCC C956
HGNC 622
MGI 1914134
PubMed 22487684
RGD 1306488
UniProt Q92624
Wiki APPBP2
APPBP2is a protein interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. This gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene.APPBP2 is present as a 70-kD protein in both cytosolic and, together with APP, membrane-associated cell fractions. Immunofluorescence microscopy demonstrated that APPBP2 is present in the Golgi region and that its distribution overlaps that of APP. APPBP2 interacts with microtubules and is functionally associated with APP transport and/or processing.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Amyloid Beta Precursor Protein Binding Protein 2 (APPBP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Amyloid Beta Precursor Protein Binding Protein 2 (APPBP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Amyloid Beta Precursor Protein Binding Protein 2 (APPBP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Amyloid Beta Precursor Protein Binding Protein 2 (APPBP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Amyloid Beta Precursor Protein Binding Protein 2 (APPBP2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Amyloid Beta Precursor Protein Binding Protein 2 (APPBP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Amyloid Beta Precursor Protein Binding Protein 2 (APPBP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Amyloid Beta Precursor Protein Binding Protein 2 (APPBP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Amyloid Beta Precursor Protein Binding Protein 2 (APPBP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Amyloid Beta Precursor Protein Binding Protein 2 (APPBP2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC956Ra01 Recombinant Amyloid Beta Precursor Protein Binding Protein 2 (APPBP2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC956Ra01 Polyclonal Antibody to Amyloid Beta Precursor Protein Binding Protein 2 (APPBP2) WB; IHC; ICC; IP.
MAC956Ra21 Monoclonal Antibody to Amyloid Beta Precursor Protein Binding Protein 2 (APPBP2) WB; IHC; ICC; IP.
Assay Kits SEC956Ra ELISA Kit for Amyloid Beta Precursor Protein Binding Protein 2 (APPBP2) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "PAT1, a microtubule-interacting protein, recognizes the basolateral sorting signal of amyloid precursor protein."Proc. Natl. Acad. Sci. U.S.A. 95:14745-14750(1998) [PubMed] [Europe PMC] [Abstract]
  2. "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain."DNA Res. 3:321-329(1996) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The gamma -secretase-cleaved C-terminal fragment of amyloid precursor protein mediates signaling to the nucleus."Proc. Natl. Acad. Sci. U.S.A. 98:14979-14984(2001) [PubMed] [Europe PMC] [Abstract]