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Prolactin Releasing Hormone Receptor (PRRP)

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PRLHR; GPR10; GR3; PrRPR; Prolactin-Releasing Peptide Receptor; G Protein-Coupled Receptor 10

Prolactin Releasing Hormone Receptor (PRRP)
CCC C940
HGNC 4464
MGI 2135956
PubMed 12207968
RGD 71037
UniProt P49683
Wiki PRRP
The prolactin-releasing hormone receptor (PRRP) is a G-protein coupled receptor that binds the prolactin releasing hormone.PRLHR is a 7-transmembrane domain receptor for prolactin-releasing hormone that is highly expressed in anterior pituitary
By screening a placenta genomic DNA library, followed by 5-prime and 3-prime RACE of pituitary and adenoma cDNA libraries, Ozawa et al. (2002) isolated a full-length cDNA encoding PRLHR, which they called PRRPR. They identified multiple transcription start sites. The predicted 370-amino acid protein contains 7 hydrophobic regions. Northern blot analysis revealed expression of a 2.2-kb transcript in pituitary adenomas.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Prolactin Releasing Hormone Receptor (PRRP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Prolactin Releasing Hormone Receptor (PRRP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Prolactin Releasing Hormone Receptor (PRRP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Prolactin Releasing Hormone Receptor (PRRP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Prolactin Releasing Hormone Receptor (PRRP) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Prolactin Releasing Hormone Receptor (PRRP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Prolactin Releasing Hormone Receptor (PRRP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Prolactin Releasing Hormone Receptor (PRRP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Prolactin Releasing Hormone Receptor (PRRP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Prolactin Releasing Hormone Receptor (PRRP) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Prolactin Releasing Hormone Receptor (PRRP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Prolactin Releasing Hormone Receptor (PRRP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Prolactin Releasing Hormone Receptor (PRRP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Prolactin Releasing Hormone Receptor (PRRP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Prolactin Releasing Hormone Receptor (PRRP) ELISA Kit Customized Service Offer
  1. "Cloning and chromosomal mapping of three novel genes, GPR9, GPR10, and GPR14, encoding receptors related to interleukin 8, neuropeptide Y, and somatostatin receptors."Genomics 29:335-344(1995) [PubMed] [Europe PMC] [Abstract]
  2. "A prolactin-releasing peptide in the brain."Nature 393:272-276(1998) [PubMed] [Europe PMC] [Abstract]
  3. "Transcriptional regulation of the human PRL-releasing peptide (PrRP) receptor gene by a dopamine 2 receptor agonist: cloning and characterization of the human PrRP receptor gene and its promoter region."Mol. Endocrinol. 16:785-798(2002) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and comparative analysis of human chromosome 10." Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Tissue distribution of prolactin-releasing peptide (PrRP) and its receptor."Regul. Pept. 83:1-10(1999) [PubMed] [Europe PMC] [Abstract]
  7. "The carboxyl terminus of the prolactin-releasing peptide receptor interacts with PDZ domain proteins involved in alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor clustering."Mol. Pharmacol. 60:916-923(2001) [PubMed] [Europe PMC] [Abstract]