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Oxoeicosanoid Receptor 1 (OXER1)

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OXE-R1; GPCR; GPR170; TG1019; 5-Oxo-ETE Acid G-Protein-Coupled Receptor 1; G-protein coupled receptor 170; G-protein coupled receptor R527

Oxoeicosanoid Receptor 1 (OXER1)
CCC C927
HGNC 24884
PubMed 23643940
UniProt Q8TDS5
Wiki OXER1
The oxoeicosanoids are nonclassic eicosanoids, derived from arachidonic acid (AA). Lipoxygenase produces 5-HETE from AA; a dehydrogenase produces oxoeicosanoids from 5-HETE.
Oxoeicosanoid receptor 1 is a protein Belongs to the G-protein coupled receptor 1 family.Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE), 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins.Expressed in various tissues except brain. xpression is more intense in liver, kidney, peripheral leukocyte, lung, and spleen than in other tissues. Highly expressed in eosinophils, neutrophils, and lung macrophages.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Oxoeicosanoid Receptor 1 (OXER1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Oxoeicosanoid Receptor 1 (OXER1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Oxoeicosanoid Receptor 1 (OXER1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Oxoeicosanoid Receptor 1 (OXER1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Oxoeicosanoid Receptor 1 (OXER1) ELISA Kit Customized Service Offer
  1. "Identification of a novel human eicosanoid receptor coupled to G(i/o)."J. Biol. Chem. 277:31459-31465(2002) [PubMed] [Europe PMC] [Abstract]
  2. "Expression and characterization of a 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid receptor highly expressed on human eosinophils and neutrophils."Mol. Pharmacol. 63:471-477(2003) [PubMed] [Europe PMC] [Abstract]
  3. "Identification of G protein-coupled receptor genes from the human genome sequence."FEBS Lett. 520:97-101(2002) [PubMed] [Europe PMC] [Abstract]
  4. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]