Selenophosphate Synthetase 1 (SEPHS1)
[Edit]SPS1; SPS; SELD; Selenide, water dikinase 1; Selenium donor protein 1
-92889.jpg)
Selenide, water dikinase 1 is an enzyme that synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, which is co-translationally incorporated into selenoproteins at in-frame UGA codons.
Synthesizes selenophosphate from selenide and ATP. ATP + selenide + H2O = AMP + selenophosphate + phosphate.
The conserved active site Cys (or selenocysteine) residue in position 29 is replaced by a Thr. However, as function in selenoprotein synthesis is proven, it is possible Cys-31 is the active site.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Selenophosphate Synthetase 1 (SEPHS1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Selenophosphate Synthetase 1 (SEPHS1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Selenophosphate Synthetase 1 (SEPHS1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Selenophosphate Synthetase 1 (SEPHS1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Selenophosphate Synthetase 1 (SEPHS1) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Selenophosphate Synthetase 1 (SEPHS1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Selenophosphate Synthetase 1 (SEPHS1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Selenophosphate Synthetase 1 (SEPHS1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Selenophosphate Synthetase 1 (SEPHS1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Selenophosphate Synthetase 1 (SEPHS1) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Selenophosphate Synthetase 1 (SEPHS1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Selenophosphate Synthetase 1 (SEPHS1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Selenophosphate Synthetase 1 (SEPHS1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Selenophosphate Synthetase 1 (SEPHS1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Selenophosphate Synthetase 1 (SEPHS1) | ELISA Kit Customized Service Offer |
- "Cloning and functional characterization of human selenophosphate synthetase, an essential component of selenoprotein synthesis."J. Biol. Chem. 270:21659-21664(1995) [PubMed] [Europe PMC] [Abstract]
- "Human selenophosphate synthetase 1 has five splice variants with unique interactions, subcellular localizations and expression patterns."Biochem. Biophys. Res. Commun. 397:53-58(2010) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and comparative analysis of human chromosome 10." Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]