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Stomatin (STOM)

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BND7; EPB7; EPB72; Erythrocyte Band 7 Integral Membrane Protein; Erythrocyte Membrane Protein Band 7.2

Stomatin (STOM)
CCC C876
HGNC 3383
MGI 95403
PubMed 9147127
RGD 1305109
UniProt P27105
Wiki Stomatin
Stomatinis a 32kD integral membrane protein found in the red cell membrane. this protein was missing from the membrane in overhydrated hereditary stomatocytosis and this is confirmed by others . It is found in virtually all human tissues and in very many animals, including simple flatworms and many bacteria: it seems to be basic in biology. The human genomic and murine genes have been isolated. The human gene maps to chromosome 9q32-34 . Prohaska and others have found that the stomatin protein molecules seems to assemble together like bricks; and that it is linked up to the scaffolding of the cell ; and that it is assocuiated with the cholesterol+sphingomyelin-rich material of the cell membrane, possibly forming isolated domains commonly known as 'rafts'.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Stomatin (STOM) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Stomatin (STOM) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Stomatin (STOM) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Stomatin (STOM) CLIA Kit Customized Service Offer
n/a ELISA Kit for Stomatin (STOM) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Stomatin (STOM) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Stomatin (STOM) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Stomatin (STOM) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Stomatin (STOM) CLIA Kit Customized Service Offer
n/a ELISA Kit for Stomatin (STOM) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Stomatin (STOM) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Stomatin (STOM) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Stomatin (STOM) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Stomatin (STOM) CLIA Kit Customized Service Offer
n/a ELISA Kit for Stomatin (STOM) ELISA Kit Customized Service Offer
  1. "Cloning and nucleotide sequence of cDNA encoding human erythrocyte band 7 integral membrane protein."Biochim. Biophys. Acta 1090:123-124(1991) [PubMed] [Europe PMC] [Abstract]
  2. "Isolation of cDNA coding for an ubiquitous membrane protein deficient in high Na+, low K+ stomatocytic erythrocytes."Blood 79:1593-1601(1992) [PubMed] [Europe PMC] [Abstract]
  3. "The organization of the gene (EPB72) encoding the human erythrocyte band 7 integral membrane protein (protein 7.2b)."Genomics 30:521-528(1995) [PubMed] [Europe PMC] [Abstract]
  4. "Structure, organization, and expression of the human band 7.2b gene, a candidate gene for hereditary hydrocytosis."J. Biol. Chem. 270:26358-26363(1995) [PubMed] [Europe PMC] [Abstract]
  5. "DNA sequence and analysis of human chromosome 9." Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Identification of the phosphorylation site on human erythrocyte band 7 integral membrane protein: implications for a monotopic protein structure."Biochim. Biophys. Acta 1151:149-152(1993) [PubMed] [Europe PMC] [Abstract]
  8. "Colocalization of stomatin (band 7.2b) and actin microfilaments in UAC epithelial cells."Eur. J. Cell Biol. 73:281-285(1997) [PubMed] [Europe PMC] [Abstract]
  9. "Isolation, molecular characterization, and tissue-specific expression of a novel putative G protein-coupled receptor."Biochim. Biophys. Acta 1395:301-308(1998) [PubMed] [Europe PMC] [Abstract]
  10. "Oligomeric nature of the integral membrane protein stomatin."J. Biol. Chem. 273:17221-17226(1998) [PubMed] [Europe PMC] [Abstract]
  11. "Cysteine 29 is the major palmitoylation site on stomatin."FEBS Lett. 449:101-104(1999) [PubMed] [Europe PMC] [Abstract]
  12. "Stomatin is a major lipid-raft component of platelet alpha granules."Blood 100:897-904(2002) [PubMed] [Europe PMC] [Abstract]
  13. "Proteomic analysis of early melanosomes: identification of novel melanosomal proteins."J. Proteome Res. 2:69-79(2003) [PubMed] [Europe PMC] [Abstract]
  14. "Characterization of the stomatin domain involved in homo-oligomerization and lipid raft association."J. Biol. Chem. 281:23349-23356(2006) [PubMed] [Europe PMC] [Abstract]
  15. "Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes."J. Proteome Res. 5:3135-3144(2006) [PubMed] [Europe PMC] [Abstract]
  16. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  17. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  18. "Stomatin interacts with GLUT1/SLC2A1, band 3/SLC4A1, and aquaporin-1 in human erythrocyte membrane domains."Biochim. Biophys. Acta 1828:956-966(2013) [PubMed] [Europe PMC] [Abstract]
  19. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]