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Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. It is highly similar in sequence to both ezrin and moesin. The radixin gene has been localized by fluorescence in situ hybridization to 11q23. A truncated version representing a pseudogene (RDXP2) was assigned to Xp21.3. Another pseudogene that seemed to lack introns (RDXP1) was mapped to 11p by Southern and PCR analyses.
The major full-length protein contains 627 amino acids forming 3 known functional domains: an N-terminal FERM domain that localizes the protein to the plasma membrane, a central helical alpha-domain, and a C-terminal actin-binding domain. By immunohistochemical analysis of mouse inner ear.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPC774Hu01 | Recombinant Radixin (RDX) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAC774Hu01 | Polyclonal Antibody to Radixin (RDX) | WB; IHC; ICC; IP. |
| Assay Kits | SEC774Hu | ELISA Kit for Radixin (RDX) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Radixin (RDX) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Radixin (RDX) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Radixin (RDX) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Radixin (RDX) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Radixin (RDX) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Radixin (RDX) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Radixin (RDX) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Radixin (RDX) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Radixin (RDX) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Radixin (RDX) | ELISA Kit Customized Service Offer |
- "Molecular cloning, cDNA sequence, and chromosomal assignment of the human radixin gene and two dispersed pseudogenes."Genomics 16:199-206(1993) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "Mutations of the RDX gene cause nonsyndromic hearing loss at the DFNB24 locus."Hum. Mutat. 28:417-423(2007) [PubMed] [Europe PMC] [Abstract]
- "Human chromosome 11 DNA sequence and analysis including novel gene identification." Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "NHE-RF, a regulatory cofactor for Na(+)-H+ exchange, is a common interactor for merlin and ERM (MERM) proteins."J. Biol. Chem. 273:1273-1276(1998) [PubMed] [Europe PMC] [Abstract]
- "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
- "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]