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Paralemmin (PALM)

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Paralemmin (PALM)
CCC C710
HGNC 8594
MGI 1261814
PubMed 9813098
RGD 620341
UniProt O75781
Paralemmin is a member of the paralemmin protein family. PALM has a highly conserved coiled-coil N terminus that displays a periodicity of acidic, basic, hydrophobic, and glutamine residues, as well as 2 potential leucine zippers.
PALM has a central motif similar to a sequence found in lipid-anchored SNAREs that is involved in endoplasmic reticulum-Golgi transport. The C terminus of PALM contains a cluster of basic residues, which likely contribute to membrane association, putative palmitoylated cysteines, and a prenylation consensus motif. PALM also has phosphorylation motifs for several serine/threonine kinases. The 5-prime untranslated regions of the chicken, mouse, and human transcripts are GC rich.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC710Hu01 Recombinant Paralemmin (PALM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC710Hu01 Polyclonal Antibody to Paralemmin (PALM) WB; IHC; ICC; IP.
MAC710Hu21 Monoclonal Antibody to Paralemmin (PALM) WB; IHC; ICC; IP.
Assay Kits SEC710Hu ELISA Kit for Paralemmin (PALM) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Paralemmin (PALM) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Paralemmin (PALM) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Paralemmin (PALM) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Paralemmin (PALM) CLIA Kit Customized Service Offer
n/a ELISA Kit for Paralemmin (PALM) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Paralemmin (PALM) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Paralemmin (PALM) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Paralemmin (PALM) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Paralemmin (PALM) CLIA Kit Customized Service Offer
n/a ELISA Kit for Paralemmin (PALM) ELISA Kit Customized Service Offer
  1. "Structure of the human paralemmin gene (PALM), mapping to human chromosome 19p13.3 and mouse chromosome 10, and exclusion of coding mutations in grizzled, mocha, jittery, and hesitant mice."Genomics 49:462-466(1998) [PubMed] [Europe PMC] [Abstract]
  2. "Paralemmin, a prenyl-palmitoyl-anchored phosphoprotein abundant in neurons and implicated in plasma membrane dynamics and cell process formation."J. Cell Biol. 143:795-813(1998) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain."DNA Res. 3:321-329(1996) [PubMed] [Europe PMC] [Abstract]
  6. "Regulation of dendritic branching and filopodia formation in hippocampal neurons by specific acylated protein motifs."Mol. Biol. Cell 15:2205-2217(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Paralemmin interacts with D3 dopamine receptors: implications for membrane localization and cAMP signaling."Arch. Biochem. Biophys. 446:60-68(2006) [PubMed] [Europe PMC] [Abstract]
  8. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  9. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  10. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  11. "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
  12. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]