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Neuronal Cell Adhesion Molecule (NRCAM)

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Bravo; NgCAM-Related Cell Adhesion Molecule; Neuronal surface protein Bravo

Neuronal Cell Adhesion Molecule (NRCAM)
CCC C668
HGNC 7994
MGI 104750
PubMed 16123759
RGD 3209
UniProt Q92823
Wiki NRCAM
Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. Neuronal cell adhesion molecule is a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. This gene is also expressed in non-neural tissues and may play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of this gene have been associated with autism and addiction vulnerability. Alternative splicing results in multiple transcript variants encoding different isoforms.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC668Hu01 Recombinant Neuronal Cell Adhesion Molecule (NRCAM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC668Hu01 Polyclonal Antibody to Neuronal Cell Adhesion Molecule (NRCAM) WB; IHC; ICC; IP.
Assay Kits SEC668Hu ELISA Kit for Neuronal Cell Adhesion Molecule (NRCAM) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Neuronal Cell Adhesion Molecule (NRCAM) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Neuronal Cell Adhesion Molecule (NRCAM) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Neuronal Cell Adhesion Molecule (NRCAM) Polyclonal Antibody Customized Service Offer
Assay Kits SEC668Mu ELISA Kit for Neuronal Cell Adhesion Molecule (NRCAM) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Neuronal Cell Adhesion Molecule (NRCAM) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Neuronal Cell Adhesion Molecule (NRCAM) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Neuronal Cell Adhesion Molecule (NRCAM) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Neuronal Cell Adhesion Molecule (NRCAM) CLIA Kit Customized Service Offer
n/a ELISA Kit for Neuronal Cell Adhesion Molecule (NRCAM) ELISA Kit Customized Service Offer
  1. "Characterization of a highly conserved human homolog to the chicken neural cell surface protein Bravo/Nr-CAM that maps to chromosome band 7q31."Genomics 35:456-465(1996) [PubMed] [Europe PMC] [Abstract]
  2. "The complete sequence of the human locus for NgCAM-related cell adhesion molecule reveals a novel alternative exon in chick and man and conserved genomic organization for the L1 subfamily."Gene 273:115-122(2001) [PubMed] [Europe PMC] [Abstract]
  3. "Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."DNA Res. 4:141-150(1997) [PubMed] [Europe PMC] [Abstract]
  4. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
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  6. "Human chromosome 7: DNA sequence and biology." Science 300:767-772(2003) [PubMed] [Europe PMC] [Abstract]
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  8. "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."J. Proteome Res. 4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
  9. "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
  10. "A strategy for precise and large scale identification of core fucosylated glycoproteins."Mol. Cell. Proteomics 8:913-923(2009) [PubMed] [Europe PMC] [Abstract]
  11. "Myocilin mediates myelination in the peripheral nervous system through ErbB2/3 signaling."J. Biol. Chem. 288:26357-26371(2013) [PubMed] [Europe PMC] [Abstract]
  12. "Solution structure of the first fibronectin type III domain of human KIAA0343 protein."Submitted (NOV-2003) to the PDB data bank
  13. "Solution structure of the third fibronectin III domain of human KIAA0343 protein."Submitted (NOV-2003) to the PDB data bank
  14. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]