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Neuroplastin (NPTN)

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SDR1; GP55; GP65; SDFR1; np55; np65; Stromal Cell Derived Factor Receptor 1

Neuroplastin (NPTN)
CCC C666
HGNC 17867
MGI 108077
PubMed 10759566
RGD 620296
UniProt Q9Y639
Wiki NPTN
Neuroplastin is a type I transmembrane protein belonging to the Ig superfamily. The protein is believed to be involved in cell-cell interactions or cell-substrate interactions. The alpha and beta transcripts show differential localization within the brain.
The deduced mature Gp55 and Gp65 proteins contain 253 and 365 amino acid residues with calculated molecular masses of 28.8 and 41.4 kD, respectively. Both species contain a single putative membrane spanning domain, and Gp55 has 2 extracellular Ig domains whereas Gp65 has 3 extracellular Ig domains. Gp55 shares similarity with basigin Ig domain proteins. Immunocytochemical studies localized Gp55 and Gp65 to the cell membrane in HEK293 cells.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC666Hu01 Recombinant Neuroplastin (NPTN) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC666Hu01 Polyclonal Antibody to Neuroplastin (NPTN) WB; IHC; ICC; IP.
MAC666Hu21 Monoclonal Antibody to Neuroplastin (NPTN) WB; IHC; ICC; IP.
Assay Kits SEC666Hu ELISA Kit for Neuroplastin (NPTN) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Neuroplastin (NPTN) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Neuroplastin (NPTN) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Neuroplastin (NPTN) Polyclonal Antibody Customized Service Offer
Assay Kits SEC666Mu ELISA Kit for Neuroplastin (NPTN) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Neuroplastin (NPTN) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Neuroplastin (NPTN) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Neuroplastin (NPTN) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Neuroplastin (NPTN) CLIA Kit Customized Service Offer
n/a ELISA Kit for Neuroplastin (NPTN) ELISA Kit Customized Service Offer
  1. "Isoform specific expression of the SDR-1 protein, alpha and beta in subregions of adult rodent brain."Biomed. Res. 20:43-49(1999)
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Signal peptide prediction based on analysis of experimentally verified cleavage sites."Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The immunolocalization of the synaptic glycoprotein neuroplastin differs substantially between the human and the rodent brain."Brain Res. 1134:107-112(2007) [PubMed] [Europe PMC] [Abstract]
  6. "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
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  8. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]