≡

Germ Cell Nuclear Factor (GCNF)

[Edit]

NR6A1; NR6-A1; GCNF1; NR61; RTR; Nuclear Receptor Subfamily 6,Group A,Member 1; Retinoid receptor-related testis-specific receptor

Germ Cell Nuclear Factor (GCNF)
CCC C509
HGNC 7985
MGI 1352459
PubMed 16155958
RGD 1564740
UniProt Q15406
Wiki GCNF
The germ cell nuclear factor (GCNF) protein, also known as RTR (retinoid receptor-related testis-associated receptor), is a member of the nuclear receptor family of intracellular transcription factors and is encoded by the NR6A1 gene (nuclear receptor subfamily 6, group A, member 1).In adults, GCNH is expressed mainly in the germ cells of gonads and is involved in the regulation of embryogenesis and germ cell differentiation.
Its expression pattern suggests that it may be involved in neurogenesis and germ cell development. The protein can homodimerize and bind DNA, but in vivo targets have not been identified. The gene expresses three alternatively spliced transcript variants.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC509Hu01 Recombinant Germ Cell Nuclear Factor (GCNF) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC509Hu01 Polyclonal Antibody to Germ Cell Nuclear Factor (GCNF) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Germ Cell Nuclear Factor (GCNF) CLIA Kit Customized Service Offer
n/a ELISA Kit for Germ Cell Nuclear Factor (GCNF) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Germ Cell Nuclear Factor (GCNF) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Germ Cell Nuclear Factor (GCNF) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Germ Cell Nuclear Factor (GCNF) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Germ Cell Nuclear Factor (GCNF) CLIA Kit Customized Service Offer
n/a ELISA Kit for Germ Cell Nuclear Factor (GCNF) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Germ Cell Nuclear Factor (GCNF) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Germ Cell Nuclear Factor (GCNF) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Germ Cell Nuclear Factor (GCNF) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Germ Cell Nuclear Factor (GCNF) CLIA Kit Customized Service Offer
n/a ELISA Kit for Germ Cell Nuclear Factor (GCNF) ELISA Kit Customized Service Offer
  1. "Characterization of the human germ cell nuclear factor gene."Biochim. Biophys. Acta 1309:179-182(1996) [PubMed] [Europe PMC] [Abstract]
  2. "cDNA cloning of two closely related forms of human germ cell nuclear factor (GCNF)."Biochim. Biophys. Acta 1352:13-17(1997) [PubMed] [Europe PMC] [Abstract]
  3. "Cloning of the human orphan receptor germ cell nuclear factor/retinoid receptor-related testis-associated receptor and its differential regulation during embryonal carcinoma cell differentiation."J. Mol. Endocrinol. 18:167-176(1997) [PubMed] [Europe PMC] [Abstract]
  4. "Cloning, expression analysis and chromosomal localization of the human nuclear receptor gene GCNF."FEBS Lett. 424:73-78(1998) [PubMed] [Europe PMC] [Abstract]
  5. "Cloning of the human NCNF gene."J. Recept. Signal Transduct. 18:1-13(1998) [PubMed] [Europe PMC] [Abstract]
  6. "DNA sequence and analysis of human chromosome 9." Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  8. "RAP80: a novel nuclear protein that interacts with the retinoid-related testis-associated receptor."J. Biol. Chem. 277:32379-32388(2002) [PubMed] [Europe PMC] [Abstract]