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Formin Binding Protein 1 (FNBP1)

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FBP17

Formin Binding Protein 1 (FNBP1)
CCC C483
HGNC 17069
MGI 109606
PubMed 14596906
RGD 621350
UniProt Q96RU3
Wiki FNBP1

Formin-binding protein 1 is a member of the formin-binding-protein family. The protein contains an N-terminal Fer/Cdc42-interacting protein 4 (CIP4) homology (FCH) domain followed by a coiled-coil domain, a proline-rich motif, a second coiled-coil domain, a Rho family protein-binding domain (RBD), and a C-terminal SH3 domain. This protein binds sorting nexin 2 (SNX2), tankyrase (TNKS), and dynamin; an interaction between this protein and formin has not been demonstrated yet in human. Very highly expressed in the epithelial cells of the gastrointestinal tract, respiratory, reproductive and urinary systems. Also highly expressed in brown adipose tissue, cardiomyocytes, enteric ganglia and glucagon producing cells of the pancreas. Expressed in germ cells of the testis and all regions of the brain.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC483Hu01 Recombinant Formin Binding Protein 1 (FNBP1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC483Hu01 Polyclonal Antibody to Formin Binding Protein 1 (FNBP1) WB; IHC; ICC; IP.
MAC483Hu22 Monoclonal Antibody to Formin Binding Protein 1 (FNBP1) WB; IHC; ICC; IP.
Assay Kits SEC483Hu ELISA Kit for Formin Binding Protein 1 (FNBP1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Formin Binding Protein 1 (FNBP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Formin Binding Protein 1 (FNBP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Formin Binding Protein 1 (FNBP1) Polyclonal Antibody Customized Service Offer
Assay Kits SEC483Mu ELISA Kit for Formin Binding Protein 1 (FNBP1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Formin Binding Protein 1 (FNBP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Formin Binding Protein 1 (FNBP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Formin Binding Protein 1 (FNBP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Formin Binding Protein 1 (FNBP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Formin Binding Protein 1 (FNBP1) ELISA Kit Customized Service Offer
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  4. "DNA sequence and analysis of human chromosome 9." Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Rich, a rho GTPase-activating protein domain-containing protein involved in signaling by Cdc42 and Rac1."J. Biol. Chem. 276:35060-35070(2001) [PubMed] [Europe PMC] [Abstract]
  7. "Identification of interaction partners of the cytosolic polyproline region of CD95 ligand (CD178)."FEBS Lett. 519:50-58(2002) [PubMed] [Europe PMC] [Abstract]
  8. "The formin-binding protein 17, FBP17, binds via a TNKS binding motif to tankyrase, a protein involved in telomere maintenance."FEBS Lett. 554:10-16(2003) [PubMed] [Europe PMC] [Abstract]
  9. "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry."Anal. Chem. 76:2763-2772(2004) [PubMed] [Europe PMC] [Abstract]
  10. "A novel dynamin-associating molecule, formin-binding protein 17, induces tubular membrane invaginations and participates in endocytosis."J. Biol. Chem. 279:40091-40099(2004) [PubMed] [Europe PMC] [Abstract]
  11. "AKAP350 interaction with cdc42 interacting protein 4 at the Golgi apparatus."Mol. Biol. Cell 15:2771-2781(2004) [PubMed] [Europe PMC] [Abstract]
  12. "Dynamin and the actin cytoskeleton cooperatively regulate plasma membrane invagination by BAR and F-BAR proteins."Dev. Cell 9:791-804(2005) [PubMed] [Europe PMC] [Abstract]
  13. "Regulation of FasL expression: a SH3 domain containing protein family involved in the lysosomal association of FasL."Cell. Signal. 18:1327-1337(2006) [PubMed] [Europe PMC] [Abstract]
  14. "The diaphanous-related formin DAAM1 collaborates with the Rho GTPases RhoA and Cdc42, CIP4 and Src in regulating cell morphogenesis and actin dynamics."Exp. Cell Res. 312:2180-2194(2006) [PubMed] [Europe PMC] [Abstract]
  15. "Coordination between the actin cytoskeleton and membrane deformation by a novel membrane tubulation domain of PCH proteins is involved in endocytosis."J. Cell Biol. 172:269-279(2006) [PubMed] [Europe PMC] [Abstract]
  16. "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."Nat. Biotechnol. 24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
  17. "Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment."J. Proteome Res. 7:5167-5176(2008) [PubMed] [Europe PMC] [Abstract]
  18. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  19. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  20. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  21. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  22. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  23. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  24. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  25. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  26. "Curved EFC/F-BAR-domain dimers are joined end to end into a filament for membrane invagination in endocytosis." Cell 129:761-772(2007) [PubMed] [Europe PMC] [Abstract]