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Dental enamel is a highly mineralized tissue with 85% of its volume occupied by unusually large, highly organized, hydroxyapatite crystals. This highly organized and unusual structure is thought to be rigorously controlled in ameloblasts through the interaction of a number of organic matrix molecules that include enamelin, amelogenin (AMELX), ameloblastin (AMBN), tuftelin, dentine sialophosphoprotein (DSPP), and a variety of enzymes.
Enamelin is the largest protein in the enamel matrix of developing teeth and comprises approximately 5% of total enamel matrix protein.The current description of enamelin is a protein coded at 4q13.3 and is a modulator for mineral formation and crystal elongation in enamel. Significant proteins in enamel are amelogenins and ameloblastins.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Enamelin (ENAM) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Enamelin (ENAM) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Enamelin (ENAM) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Enamelin (ENAM) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Enamelin (ENAM) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Enamelin (ENAM) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Enamelin (ENAM) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Enamelin (ENAM) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Enamelin (ENAM) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Enamelin (ENAM) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Enamelin (ENAM) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Enamelin (ENAM) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Enamelin (ENAM) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Enamelin (ENAM) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Enamelin (ENAM) | ELISA Kit Customized Service Offer |
- "Dietary change and adaptive evolution of enamelin in humans and among primates."Genetics 178:1595-1603(2008) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Enamelin maps to human chromosome 4q21 within the autosomal dominant amelogenesis imperfecta locus."Eur. J. Oral Sci. 108:353-358(2000) [PubMed] [Europe PMC] [Abstract]
- "Mutation of the gene encoding the enamel-specific protein, enamelin, causes autosomal-dominant amelogenesis imperfecta."Hum. Mol. Genet. 10:1673-1677(2001) [PubMed] [Europe PMC] [Abstract]
- "A nonsense mutation in the enamelin gene causes local hypoplastic autosomal dominant amelogenesis imperfecta (AIH2)."Hum. Mol. Genet. 11:1069-1074(2002) [PubMed] [Europe PMC] [Abstract]
- "Novel ENAM mutation responsible for autosomal recessive amelogenesis imperfecta and localised enamel defects."J. Med. Genet. 40:900-906(2003) [PubMed] [Europe PMC] [Abstract]