Synuclein Beta (SNCb)

Beta-synuclein  is highly homologous to alpha-synuclein. The encoded protein, which may play a role in neuronal plasticity, is abundant in neurofibrillary lesions of patients with Alzheimer's disease. This protein has been shown to be highly expressed in the substantia nigra of the brain, a region of neuronal degeneration in patients with Parkinson's disease; however, no direct relation to Parkinson's disease has been established.

Beta-synuclein is a synuclein protein found primarily in brain tissue and is seen mainly in presynaptic terminals. Beta-synuclein is predominantly expressed in the neocortex, hippocampus, striatum, thalamus, and cerebellum. It is not found in Lewy bodies, but it is associated with hippocampal pathology in Parkinson's disease and dementia with Lewy bodies.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Synuclein Beta (SNCb) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Synuclein Beta (SNCb) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Synuclein Beta (SNCb) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Synuclein Beta (SNCb) CLIA Kit Customized Service Offer
n/a ELISA Kit for Synuclein Beta (SNCb) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Synuclein Beta (SNCb) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Synuclein Beta (SNCb) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Synuclein Beta (SNCb) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Synuclein Beta (SNCb) CLIA Kit Customized Service Offer
n/a ELISA Kit for Synuclein Beta (SNCb) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Synuclein Beta (SNCb) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Synuclein Beta (SNCb) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Synuclein Beta (SNCb) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Synuclein Beta (SNCb) CLIA Kit Customized Service Offer
n/a ELISA Kit for Synuclein Beta (SNCb) ELISA Kit Customized Service Offer
  1. "Identification of two distinct synucleins from human brain."FEBS Lett. 345:27-32(1994) [PubMed] [Europe PMC] [Abstract]
  2. "Genomic organization and expression of the human beta-synuclein gene (SNCB)."Genomics 54:173-175(1998) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]