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Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2)

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bHLHe1; Class E basic helix-loop-helix protein 1

Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2)
CCC C301
HGNC 16876
MGI 107188
PubMed 10640708
RGD 2154
UniProt Q9HBZ2
Wiki ARNT2

2 is a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting addition roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC301Hu01 Recombinant Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC301Hu01 Polyclonal Antibody to Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2) ELISA Kit Customized Service Offer
  1. "Aryl hydrocarbon receptor nuclear translocator 2 (ARNT2): structure, gene mapping, polymorphisms, and candidate evaluation for human orofacial clefts."Teratology 66:85-90(2002) [PubMed] [Europe PMC] [Abstract]
  2. "Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."DNA Res. 4:141-150(1997) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  7. "ARNT2 mutation causes hypopituitarism, post-natal microcephaly, visual and renal anomalies." Brain 136:3096-3105(2013) [PubMed] [Europe PMC] [Abstract]