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Amine Oxidase, Copper Containing 3 (AOC3)

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VAP1; HPAO; SSAO; Membrane primary amine oxidase; Vascular Adhesion Protein 1; Semicarbazide-Sensitive Amine Oxidase; Copper-Containing Amine Oxygen Oxidoreductase

Amine Oxidase, Copper Containing 3 (AOC3)
CCC C298
HGNC 550
MGI 1306797
PubMed 15664163
RGD 62058
UniProt Q16853
Wiki AOC3

SSAO can deaminate short-chain primary amines, but is insensitive to MAO inhibitors. Semicarbazide inhibits the enzyme, in addition to other hydrazines, hydroxylamine and propargylamine. However, hydrazines are weak inhibitors and stronger inhibitors have been developed.

SSAO is found in the smooth muscle of blood vessels and various other tissues. The physiological function of SSAO is not well understood. Development of blood vessels, lipolysis regulation, and detoxication are suggested. It may function as a scavenger enzyme to assist MAO. However, the oxidation process generates harmful products that may be involved in causing atherosclerosis and vascular damage in diabetes.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins EPC298Hu61 Eukaryotic Amine Oxidase, Copper Containing 3 (AOC3) Positive Control; Immunogen; SDS-PAGE; WB.
APC298Hu61 Active Amine Oxidase, Copper Containing 3 (AOC3) Cell culture; Activity Assays.
Antibodies n/a Monoclonal Antibody to Amine Oxidase, Copper Containing 3 (AOC3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Amine Oxidase, Copper Containing 3 (AOC3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Amine Oxidase, Copper Containing 3 (AOC3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Amine Oxidase, Copper Containing 3 (AOC3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC298Mu01 Recombinant Amine Oxidase, Copper Containing 3 (AOC3) Positive Control; Immunogen; SDS-PAGE; WB.
RPC298Mu02 Recombinant Amine Oxidase, Copper Containing 3 (AOC3) Positive Control; Immunogen; SDS-PAGE; WB.
EPC298Mu61 Eukaryotic Amine Oxidase, Copper Containing 3 (AOC3) Positive Control; Immunogen; SDS-PAGE; WB.
APC298Mu61 Active Amine Oxidase, Copper Containing 3 (AOC3) Cell culture; Activity Assays.
Antibodies PAC298Mu01 Polyclonal Antibody to Amine Oxidase, Copper Containing 3 (AOC3) WB; IHC; ICC; IP.
PAC298Mu02 Polyclonal Antibody to Amine Oxidase, Copper Containing 3 (AOC3) WB; IHC; ICC; IP.
Assay Kits SEC298Mu ELISA Kit for Amine Oxidase, Copper Containing 3 (AOC3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Amine Oxidase, Copper Containing 3 (AOC3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Amine Oxidase, Copper Containing 3 (AOC3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Amine Oxidase, Copper Containing 3 (AOC3) Polyclonal Antibody Customized Service Offer
Assay Kits SEC298Ra ELISA Kit for Amine Oxidase, Copper Containing 3 (AOC3) Enzyme-linked immunosorbent assay for Antigen Detection.
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  14. "Crystal structure of the human vascular adhesion protein-1: unique structural features with functional implications."Protein Sci. 14:1964-1974(2005) [PubMed] [Europe PMC] [Abstract]