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Bromodomain Containing Protein 8 (BRD8)

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SMAP; p120; SMAP2; Skeletal muscle abundant protein 2; Thyroid hormone receptor coactivating protein of 120 kDa

Bromodomain Containing Protein 8 (BRD8)
CCC C253
HGNC 19874
MGI 1925906
PubMed 19787264
UniProt Q9H0E9
Wiki BRD8

Bromodomain-containing protein 8 is a protein encoded by this gene interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid hormone-dependent activation from thyroid response elements. This protein contains a bromodomain and is thought to be a nuclear receptor coactivator. Three alternatively spliced transcript variants that encode distinct isoforms have been identified.This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Bromodomain Containing Protein 8 (BRD8) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Bromodomain Containing Protein 8 (BRD8) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Bromodomain Containing Protein 8 (BRD8) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Bromodomain Containing Protein 8 (BRD8) CLIA Kit Customized Service Offer
n/a ELISA Kit for Bromodomain Containing Protein 8 (BRD8) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC253Mu01 Recombinant Bromodomain Containing Protein 8 (BRD8) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC253Mu01 Polyclonal Antibody to Bromodomain Containing Protein 8 (BRD8) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Bromodomain Containing Protein 8 (BRD8) CLIA Kit Customized Service Offer
n/a ELISA Kit for Bromodomain Containing Protein 8 (BRD8) ELISA Kit Customized Service Offer
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