Thyroid Hormone Receptor Alpha (THRa)

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THR-A; NR1A1; AR7; EAR7; ERB-T1; ERBA1; NR1-A1; THRA1; THRA2; c-ERBA1; Erythroblastic Leukemia Viral Oncogene Homolog; Nuclear Receptor Subfamily 1,Group A,Member 1

Thyroid Hormone Receptor Alpha (THRa)

Thyroid hormone receptor alpha (TR-alpha)  is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported.Messenger RNA from this gene was expressed in tissue-specific fashion, with highest levels in the central nervous system and no expression in the liver. An increasing body of evidence indicated the presence of multiple thyroid hormone receptors. Many of the clinical and physiologic studies suggested the existence of multiple receptors.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC239Hu01 Recombinant Thyroid Hormone Receptor Alpha (THRa) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC239Hu01 Polyclonal Antibody to Thyroid Hormone Receptor Alpha (THRa) WB; IHC; ICC; IP.
MAC239Hu22 Monoclonal Antibody to Thyroid Hormone Receptor Alpha (THRa) WB; IHC; ICC; IP.
Assay Kits SEC239Hu ELISA Kit for Thyroid Hormone Receptor Alpha (THRa) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Thyroid Hormone Receptor Alpha (THRa) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Thyroid Hormone Receptor Alpha (THRa) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Thyroid Hormone Receptor Alpha (THRa) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Thyroid Hormone Receptor Alpha (THRa) CLIA Kit Customized Service Offer
n/a ELISA Kit for Thyroid Hormone Receptor Alpha (THRa) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC239Ra01 Recombinant Thyroid Hormone Receptor Alpha (THRa) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC239Ra01 Polyclonal Antibody to Thyroid Hormone Receptor Alpha (THRa) WB; IHC; ICC; IP.
MAC239Ra21 Monoclonal Antibody to Thyroid Hormone Receptor Alpha (THRa) WB; IHC; ICC; IP.
Assay Kits SEC239Ra ELISA Kit for Thyroid Hormone Receptor Alpha (THRa) Enzyme-linked immunosorbent assay for Antigen Detection.
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  19. "Gaining ligand selectivity in thyroid hormone receptors via entropy."Proc. Natl. Acad. Sci. U.S.A. 106:20717-20722(2009) [PubMed] [Europe PMC] [Abstract]