Transforming Growth Factor Beta Receptor III (TGFbR3)
[Edit]BGCAN; Beta-Glycan; Betaglycan; Proteoglycan
-92119.jpg)
Betaglycan also known as Transforming growth factor, beta receptor III (TGFBR3), is a cell-surface chondroitin sulfate / heparan sulfate proteoglycan >300 kDa in molecular weight. Betaglycan binds to various members of the TGF-beta superfamily of ligands via its core protein, and bFGF via its heparan sulfate chains. It is not involved directly in TGF-beta signal transduction but by binding to various member of the TGF-beta superfamily at the cell surface it acts as a reservoir of ligand for TGF-beta receptors.
TGF-beta is a multifunctional cytokine that modulates several tissue development and repair processes, including cell differentiation, cell cycle progression, cellular migration, adhesion, and extracellular matrix production.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Transforming Growth Factor Beta Receptor III (TGFbR3) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Transforming Growth Factor Beta Receptor III (TGFbR3) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Transforming Growth Factor Beta Receptor III (TGFbR3) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Transforming Growth Factor Beta Receptor III (TGFbR3) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Transforming Growth Factor Beta Receptor III (TGFbR3) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPC119Mu01 | Recombinant Transforming Growth Factor Beta Receptor III (TGFbR3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAC119Mu01 | Polyclonal Antibody to Transforming Growth Factor Beta Receptor III (TGFbR3) | WB; IHC; ICC; IP. |
| Assay Kits | n/a | CLIA Kit for Transforming Growth Factor Beta Receptor III (TGFbR3) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Transforming Growth Factor Beta Receptor III (TGFbR3) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPC119Ra01 | Recombinant Transforming Growth Factor Beta Receptor III (TGFbR3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAC119Ra01 | Polyclonal Antibody to Transforming Growth Factor Beta Receptor III (TGFbR3) | WB; IHC; ICC; IP. |
| Assay Kits | n/a | CLIA Kit for Transforming Growth Factor Beta Receptor III (TGFbR3) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Transforming Growth Factor Beta Receptor III (TGFbR3) | ELISA Kit Customized Service Offer |
- "Molecular cloning and characterization of the human and porcine transforming growth factor-beta type III receptors."Biochem. Biophys. Res. Commun. 189:356-362(1992) [PubMed] [Europe PMC] [Abstract]
- "Eleven single nucleotide polymorphisms and one triple nucleotide insertion of the human TGF-beta III receptor gene."J. Hum. Genet. 45:250-253(2000) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Identification of Tctex2beta, a novel dynein light chain family member that interacts with different transforming growth factor-beta receptors."J. Biol. Chem. 281:37069-37080(2006) [PubMed] [Europe PMC] [Abstract]