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Platelet Derived Growth Factor Receptor Beta (PDGFRb)

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CD140b; JTK12; PDGF-R-Beta; PDGFR; PDGFR1; CD140 antigen-like family member B; Platelet-derived growth factor receptor 1; Beta-type platelet-derived growth factor receptor

Platelet Derived Growth Factor Receptor Beta (PDGFRb)
CCC C061
HGNC 8804
MGI 97531
PubMed 23441134
RGD 3285
UniProt P09619
Wiki PDGFRB

PDGFRb is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC061Hu01 Recombinant Platelet Derived Growth Factor Receptor Beta (PDGFRb) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC061Hu01 Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) WB; IHC; ICC; IP.
MAC061Hu22 Monoclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) WB; IHC; ICC; IP.
Assay Kits SEC061Hu ELISA Kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC061Mu01 Recombinant Platelet Derived Growth Factor Receptor Beta (PDGFRb) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC061Mu01 Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) CLIA Kit Customized Service Offer
n/a ELISA Kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Platelet Derived Growth Factor Receptor Beta (PDGFRb) Recombinant Protein Customized Service Offer
Antibodies PAC061Ra01 Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) WB; IHC; ICC; IP.
Assay Kits SEC061Ra ELISA Kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Ovis aries; Ovine (Sheep)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Platelet Derived Growth Factor Receptor Beta (PDGFRb) Recombinant Protein Customized Service Offer
Antibodies PAC061Ov01 Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) CLIA Kit Customized Service Offer
n/a ELISA Kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) ELISA Kit Customized Service Offer
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  53. "Mutations in PDGFRB cause autosomal-dominant infantile myofibromatosis." Am. J. Hum. Genet. 92:1001-1007(2013) [PubMed] [Europe PMC] [Abstract]
  54. "A recurrent PDGFRB mutation causes familial infantile myofibromatosis." Am. J. Hum. Genet. 92:996-1000(2013) [PubMed] [Europe PMC] [Abstract]
  55. "Mutation of the PDGFRB gene as a cause of idiopathic basal ganglia calcification." Neurology 80:181-187(2013) [PubMed] [Europe PMC] [Abstract]