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Platelet Derived Growth Factor Receptor Beta (PDGFRb)

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CD140b; JTK12; PDGF-R-Beta; PDGFR; PDGFR1; CD140 antigen-like family member B; Platelet-derived growth factor receptor 1; Beta-type platelet-derived growth factor receptor

Platelet Derived Growth Factor Receptor Beta (PDGFRb)
CCC C061
HGNC 8804
MGI 97531
PubMed 23441134
RGD 3285
UniProt P09619
Wiki PDGFRB

PDGFRb is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC061Hu01 Recombinant Platelet Derived Growth Factor Receptor Beta (PDGFRb) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC061Hu01 Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) Testing in progress
MAC061Hu22 Monoclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) WB; IHC; ICC; IP.
Assay Kits SEC061Hu ELISA Kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC061Mu01 Recombinant Platelet Derived Growth Factor Receptor Beta (PDGFRb) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC061Mu01 Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) WB
Assay Kits n/a CLIA Kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) CLIA Kit Customized Service Offer
n/a ELISA Kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Platelet Derived Growth Factor Receptor Beta (PDGFRb) Recombinant Protein Customized Service Offer
Antibodies PAC061Ra01 Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) Testing in progress.
Assay Kits SEC061Ra ELISA Kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Ovis aries; Ovine (Sheep)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Platelet Derived Growth Factor Receptor Beta (PDGFRb) Recombinant Protein Customized Service Offer
Antibodies PAC061Ov01 Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) Testing in progress.
Assay Kits n/a CLIA Kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) CLIA Kit Customized Service Offer
n/a ELISA Kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) ELISA Kit Customized Service Offer
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  53. "Mutations in PDGFRB cause autosomal-dominant infantile myofibromatosis." Am. J. Hum. Genet. 92:1001-1007(2013) [PubMed] [Europe PMC] [Abstract]
  54. "A recurrent PDGFRB mutation causes familial infantile myofibromatosis." Am. J. Hum. Genet. 92:996-1000(2013) [PubMed] [Europe PMC] [Abstract]
  55. "Mutation of the PDGFRB gene as a cause of idiopathic basal ganglia calcification." Neurology 80:181-187(2013) [PubMed] [Europe PMC] [Abstract]