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Transforming growth factor beta 3 (TGF-beta3) is a type of protein, known as a cytokine, which is involved in cell differentiation, embryogenesis and development. It belongs to a large family of cytokines called the Transforming growth factor beta superfamily, which includes the TGF-beta; family, Bone morphogenetic proteins (BMPs), growth and differentiation factors (GDFs), inhibins and activins.
TGF-beta3 is believed to regulate molecules involved in cellular adhesion and extracellular matrix (ECM) formation during the process of palate development. Without TGF-beta3, mammals develop a deformity known as a cleft palate.This is caused by failure of epithelial cells in both sides of the developing palate to fuse.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB949Mu01 | Recombinant Transforming Growth Factor Beta 3 (TGFb3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB949Mu02 | Recombinant Transforming Growth Factor Beta 3 (TGFb3) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAB949Mu01 | Polyclonal Antibody to Transforming Growth Factor Beta 3 (TGFb3) | WB; IHC; ICC; IP. |
| PAB949Mu02 | Polyclonal Antibody to Transforming Growth Factor Beta 3 (TGFb3) | WB; IHC; ICC; IP. | |
| Assay Kits | SEB949Mu | ELISA Kit for Transforming Growth Factor Beta 3 (TGFb3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCB949Mu | CLIA Kit for Transforming Growth Factor Beta 3 (TGFb3) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB949Ra01 | Recombinant Transforming Growth Factor Beta 3 (TGFb3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| APB949Ra01 | Active Transforming Growth Factor Beta 3 (TGFb3) | Cell culture; Activity Assays. | |
| Antibodies | PAB949Ra01 | Polyclonal Antibody to Transforming Growth Factor Beta 3 (TGFb3) | WB; IHC; ICC; IP. |
| MAB949Ra21 | Monoclonal Antibody to Transforming Growth Factor Beta 3 (TGFb3) | WB; IHC; ICC; IP. | |
| Assay Kits | SEB949Ra | ELISA Kit for Transforming Growth Factor Beta 3 (TGFb3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCB949Ra | CLIA Kit for Transforming Growth Factor Beta 3 (TGFb3) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Oryctolagus cuniculus (Rabbit)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB949Rb01 | Recombinant Transforming Growth Factor Beta 3 (TGFb3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | n/a | Monoclonal Antibody to Transforming Growth Factor Beta 3 (TGFb3) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Transforming Growth Factor Beta 3 (TGFb3) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Transforming Growth Factor Beta 3 (TGFb3) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Transforming Growth Factor Beta 3 (TGFb3) | ELISA Kit Customized Service Offer |
Organism species: Sus scrofa; Porcine (Pig)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB949Po01 | Recombinant Transforming Growth Factor Beta 3 (TGFb3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAB949Po01 | Polyclonal Antibody to Transforming Growth Factor Beta 3 (TGFb3) | WB; IHC; ICC; IP. |
| MAB949Po21 | Monoclonal Antibody to Transforming Growth Factor Beta 3 (TGFb3) | WB; IHC; ICC; IP. | |
| Assay Kits | SEB949Po | ELISA Kit for Transforming Growth Factor Beta 3 (TGFb3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCB949Po | CLIA Kit for Transforming Growth Factor Beta 3 (TGFb3) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Bos taurus; Bovine (Cattle)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB949Bo01 | Recombinant Transforming Growth Factor Beta 3 (TGFb3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAB949Bo01 | Polyclonal Antibody to Transforming Growth Factor Beta 3 (TGFb3) | WB; IHC; ICC; IP. |
| Assay Kits | n/a | CLIA Kit for Transforming Growth Factor Beta 3 (TGFb3) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Transforming Growth Factor Beta 3 (TGFb3) | ELISA Kit Customized Service Offer |
- "Identification of another member of the transforming growth factor type beta gene family."Proc. Natl. Acad. Sci. U.S.A. 85:4715-4719(1988) [PubMed] [Europe PMC] [Abstract]
- "A new type of transforming growth factor-beta, TGF-beta 3."EMBO J. 7:3737-3743(1988) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and analysis of human chromosome 14." Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
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- "Mechanisms for asporin function and regulation in articular cartilage."J. Biol. Chem. 282:32185-32192(2007) [PubMed] [Europe PMC] [Abstract]
- "The crystal structure of TGF-beta 3 and comparison to TGF-beta 2: implications for receptor binding."Protein Sci. 5:1261-1271(1996) [PubMed] [Europe PMC] [Abstract]
- "Regulatory mutations in transforming growth factor-beta3 gene cause arrhythmogenic right ventricular cardiomyopathy type 1."Cardiovasc. Res. 65:366-373(2005) [PubMed] [Europe PMC] [Abstract]
- "A mutation in TGFB3 associated with a syndrome of low muscle mass, growth retardation, distal arthrogryposis and clinical features overlapping with Marfan and Loeys-Dietz syndrome."Am. J. Med. Genet. A 161A:2040-2046(2013) [PubMed] [Europe PMC] [Abstract]