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Apolipoprotein C3 (APOC3)

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Apo-C3; APOCIII; APOC-III

Apolipoprotein C3 (APOC3)
CCC B890
HGNC 610
MGI 88055
PubMed 16015281
RGD 2136
UniProt P02656
Wiki APOC3

Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed.

An increase in apoC-III levels induces the development of hypertriglyceridemia.Lately, two novel susceptibility haplotypes i.e. P2-S2-X1 and P1-S2-X1 have been discovered in ApoAI-CIII-AIV gene cluster on chromosme 11q23, who confer approximately threefold higher risk of coronary heart disease in normal as well as non-insulin diabetes mellitus.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB890Hu01 Recombinant Apolipoprotein C3 (APOC3) Positive Control; Immunogen; SDS-PAGE; WB.
APB890Hu01 Active Apolipoprotein C3 (APOC3) Cell culture; Activity Assays.
RPB890Hu02 Recombinant Apolipoprotein C3 (APOC3) Positive Control; Immunogen; SDS-PAGE; WB.
RPB890Hu03 Recombinant Apolipoprotein C3 (APOC3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB890Hu01 Polyclonal Antibody to Apolipoprotein C3 (APOC3) WB; IHC; ICC; IP.
MAB890Hu22 Monoclonal Antibody to Apolipoprotein C3 (APOC3) WB; IHC; ICC; IP.
Assay Kits SEB890Hu ELISA Kit for Apolipoprotein C3 (APOC3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB890Mu01 Recombinant Apolipoprotein C3 (APOC3) Positive Control; Immunogen; SDS-PAGE; WB.
RPB890Mu02 Recombinant Apolipoprotein C3 (APOC3) Positive Control; Immunogen; SDS-PAGE; WB.
APB890Mu01 Active Apolipoprotein C3 (APOC3) Cell culture; Activity Assays.
Antibodies PAB890Mu01 Polyclonal Antibody to Apolipoprotein C3 (APOC3) WB; IHC; ICC; IP.
PAB890Mu02 Polyclonal Antibody to Apolipoprotein C3 (APOC3) WB; IHC; ICC; IP.
MAB890Mu21 Monoclonal Antibody to Apolipoprotein C3 (APOC3) WB; IHC; ICC; IP.
Assay Kits SEB890Mu ELISA Kit for Apolipoprotein C3 (APOC3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB890Ra01 Recombinant Apolipoprotein C3 (APOC3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB890Ra01 Polyclonal Antibody to Apolipoprotein C3 (APOC3) WB; IHC; ICC; IP.
LAB890Ra71 Biotin-Linked Polyclonal Antibody to Apolipoprotein C3 (APOC3) WB; IHC; ICC.
LAB890Ra81 FITC-Linked Polyclonal Antibody to Apolipoprotein C3 (APOC3) WB; IHC; ICC; IF.
MAB890Ra21 Monoclonal Antibody to Apolipoprotein C3 (APOC3) WB; IHC; ICC; IP.
Assay Kits SEB890Ra ELISA Kit for Apolipoprotein C3 (APOC3) Enzyme-linked immunosorbent assay for Antigen Detection.
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  14. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
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  16. "Apolipoprotein C-III(Lys-58-->Glu). Identification of an apolipoprotein C-III variant in a family with hyperalphalipoproteinemia."J. Clin. Invest. 87:1724-1731(1991) [PubMed] [Europe PMC] [Abstract]