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Choline Transporter Like Protein 1 (CTL1)

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CD92; CDw92; SLC44A1; CHTL1; SLC44-A1; Solute Carrier Family 44 Member 1

Choline Transporter Like Protein 1 (CTL1)
CCC B858
HGNC 18798
MGI 2140592
PubMed 23948665
UniProt Q8WWI5
Wiki SLC44A1

Using an expression cloning approach, Wille et al. (2001) obtained a cDNA encoding CDw92. The deduced 652-amino acid CDw92 protein is 99% identical to the CTL1 protein reported by O'Regan et al. (2000). CDw92 has cytoplasmic N and C termini, 3 potential N-glycosylation sites, and a potential ITIM (immunoglobulin tyrosine-based inhibitory motif). Immunoprecipitation analysis showed that CDw92 is expressed as a 70-kD protein.

Flow cytometric analysis demonstrated expression of CDw92 on almost all B lymphocytes, most T lymphocytes, some NK cells, and some myeloid cell lines tested. Maturation of monocyte/dendritic cells resulted in downregulation of CDw92, and expression could subsequently be upregulated by interleukin-10 (IL10).

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB858Hu01 Recombinant Choline Transporter Like Protein 1 (CTL1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB858Hu01 Polyclonal Antibody to Choline Transporter Like Protein 1 (CTL1) WB; IHC; ICC; IP.
MAB858Hu21 Monoclonal Antibody to Choline Transporter Like Protein 1 (CTL1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Choline Transporter Like Protein 1 (CTL1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Choline Transporter Like Protein 1 (CTL1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Choline Transporter Like Protein 1 (CTL1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Choline Transporter Like Protein 1 (CTL1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Choline Transporter Like Protein 1 (CTL1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Choline Transporter Like Protein 1 (CTL1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Choline Transporter Like Protein 1 (CTL1) ELISA Kit Customized Service Offer
  1. "An electric lobe suppressor for a yeast choline transport mutation belongs to a new family of transporter-like proteins."Proc. Natl. Acad. Sci. U.S.A. 97:1835-1840(2000) [PubMed] [Europe PMC] [Abstract]
  2. "Characterization of CDw92 as a member of the choline transporter-like protein family regulated specifically on dendritic cells."J. Immunol. 167:5795-5804(2001) [PubMed] [Europe PMC] [Abstract]
  3. "Molecular characterization of the family of choline transporter-like proteins and their splice variants."J. Neurochem. 92:1116-1125(2005) [PubMed] [Europe PMC] [Abstract]
  4. "DNA sequence and analysis of human chromosome 9." Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  7. "The solute carrier 44A1 is a mitochondrial protein and mediates choline transport."FASEB J. 23:2749-2758(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
  9. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]