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Inhibitory Subunit Of NF Kappa B Alpha (IkBa)

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NFKBIA; IKB-A; MAD-3; NFKBI; Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells Inhibitor,Alpha; Major histocompatibility complex enhancer-binding protein MAD3

Inhibitory Subunit Of NF Kappa B Alpha (IkBa)
CCC B848
HGNC 7797
MGI 104741
PubMed 15202778
RGD 3171
UniProt P25963
Wiki IKBA

Ikappa;Balpha; (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha) is one member of a family of cellular proteins that function to inhibit the NF-kappa;B transcription factor. Ikappa;Balpha; inhibits NF-kappa;B by masking the nuclear localization signals (NLS) of NF-kappa;B proteins and keeping them sequestered in an inactive state in the cytoplasm. In addition, Ikappa;Balpha; blocks the ability of NF-kappa;B transcription factors to bind to DNA, which is required for NF-kappa;B's proper functioning. The gene encoding the Ikappa;Balpha; protein is mutated in some Hodgkin's lymphoma cells; such mutations inactivate the Ikappa;Balpha; protein, thus causing NF-kappa;B to be chronically active in the lymphoma tumor cells and this activity contributes to the malignant state of these tumor cells.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB848Hu01 Recombinant Inhibitory Subunit Of NF Kappa B Alpha (IkBa) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB848Hu01 Polyclonal Antibody to Inhibitory Subunit Of NF Kappa B Alpha (IkBa) WB; IHC; ICC; IP.
MAB848Hu22 Monoclonal Antibody to Inhibitory Subunit Of NF Kappa B Alpha (IkBa) WB; IHC; ICC; IP.
LAB848Hu71 Biotin-Linked Polyclonal Antibody to Inhibitory Subunit Of NF Kappa B Alpha (IkBa) WB; IHC; ICC.
Assay Kits SEB848Hu ELISA Kit for Inhibitory Subunit Of NF Kappa B Alpha (IkBa) Enzyme-linked immunosorbent assay for Antigen Detection.
HEB848Hu High Sensitive ELISA Kit for Inhibitory Subunit Of NF Kappa B Alpha (IkBa) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB848Mu01 Recombinant Inhibitory Subunit Of NF Kappa B Alpha (IkBa) Positive Control; Immunogen; SDS-PAGE; WB.
RPB848Mu02 Recombinant Inhibitory Subunit Of NF Kappa B Alpha (IkBa) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB848Mu01 Polyclonal Antibody to Inhibitory Subunit Of NF Kappa B Alpha (IkBa) WB; IHC; ICC; IP.
PAB848Mu02 Polyclonal Antibody to Inhibitory Subunit Of NF Kappa B Alpha (IkBa) WB; IHC; ICC; IP.
Assay Kits SEB848Mu ELISA Kit for Inhibitory Subunit Of NF Kappa B Alpha (IkBa) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Inhibitory Subunit Of NF Kappa B Alpha (IkBa) Recombinant Protein Customized Service Offer
Antibodies PAB848Ra01 Polyclonal Antibody to Inhibitory Subunit Of NF Kappa B Alpha (IkBa) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Inhibitory Subunit Of NF Kappa B Alpha (IkBa) CLIA Kit Customized Service Offer
n/a ELISA Kit for Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit Customized Service Offer
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