Vascular Endothelial Growth Factor Receptor 1 (VEGFR1)
[Edit]Flt1; Fms-Related Tyrosine Kinase 1; Vascular Permeability Factor Receptor; Fms-like tyrosine kinase 1; Tyrosine-protein kinase receptor FLT
Vascular endothelial growth factor receptor-1 was originally discovered through the screening of a human placental cDNA library . It is a receptor tyrosine kinase (RTK) specific for the angiogenic factors VEGF (VEGF-A), PlGF, and VEGF-B. VEGF R1 is expressed in two forms via alternate splicing at the pre-mRNA level: a full-length, membrane bound receptor capable of transducing signal, and a truncated, soluble receptor (sVEGF R1) capable of sequestering ligand or dimerizing with full-length receptor and preventing signal transduction.
Although VEGF R1 null mutations are lethal, deletions of the kinase domain are not, suggesting that the soluble form, or at least the extracellular domain, is all that is necessary for normal vascular development.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB818Mu01 | Recombinant Vascular Endothelial Growth Factor Receptor 1 (VEGFR1) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPB818Mu02 | Recombinant Vascular Endothelial Growth Factor Receptor 1 (VEGFR1) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAB818Mu01 | Polyclonal Antibody to Vascular Endothelial Growth Factor Receptor 1 (VEGFR1) | WB; IHC; ICC; IP. |
LAB818Mu71 | Biotin-Linked Polyclonal Antibody to Vascular Endothelial Growth Factor Receptor 1 (VEGFR1) | WB; IHC; ICC. | |
PAB818Mu02 | Polyclonal Antibody to Vascular Endothelial Growth Factor Receptor 1 (VEGFR1) | WB; IHC; ICC; IP. | |
Assay Kits | SEB818Mu | ELISA Kit for Vascular Endothelial Growth Factor Receptor 1 (VEGFR1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
SCB818Mu | CLIA Kit for Vascular Endothelial Growth Factor Receptor 1 (VEGFR1) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
Organism species: Sus scrofa; Porcine (Pig)
Organism species: Ovis aries; Ovine (Sheep)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Vascular Endothelial Growth Factor Receptor 1 (VEGFR1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Vascular Endothelial Growth Factor Receptor 1 (VEGFR1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Vascular Endothelial Growth Factor Receptor 1 (VEGFR1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | SEB818Ov | ELISA Kit for Vascular Endothelial Growth Factor Receptor 1 (VEGFR1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
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