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Cell Division Cycle Protein 23 (CDC23)

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APC8; ANAPC8; Anaphase-promoting complex subunit 8; Cyclosome subunit 8

Cell Division Cycle Protein 23 (CDC23)
CCC B771
HGNC 1724
MGI 1098815
PubMed 21990323
UniProt Q9UJX2
Wiki CDC23

The CDC23 protein shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. CDC23 is a critical regulator of cell cycle and cell growth, and may be involved in thyroid cancer initiation and progression, and may explain the different tumor biology observed by gender.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB771Hu01 Recombinant Cell Division Cycle Protein 23 (CDC23) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB771Hu01 Polyclonal Antibody to Cell Division Cycle Protein 23 (CDC23) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Cell Division Cycle Protein 23 (CDC23) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cell Division Cycle Protein 23 (CDC23) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cell Division Cycle Protein 23 (CDC23) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cell Division Cycle Protein 23 (CDC23) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cell Division Cycle Protein 23 (CDC23) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cell Division Cycle Protein 23 (CDC23) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cell Division Cycle Protein 23 (CDC23) ELISA Kit Customized Service Offer
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