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Hydroxymethylglutaryl Coenzyme A Synthase (HMGCS)

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HMGCS1; 3-Hydroxy-3-Methylglutaryl-Coenzyme A Synthase 1,Soluble; HMG-CoA Synthase

Hydroxymethylglutaryl Coenzyme A Synthase (HMGCS)
CCC B759
HGNC 5007
MGI 107592
PubMed 22459824
RGD 70970
UniProt Q01581
Wiki HMGCS

HMG-CoA synthase is an enzyme which catalyzes the reaction where Acetyl-CoA condenses with acetoacetyl-CoA to form 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA). This reaction occurs at a faster rate in patients with Diabetes Insipidus type I if left untreated.

The gene for the mitochondrial form of the enzyme has three sterol regulatory elements in the 5' flanking region . These elements are responsible for decreased transcription of the message responsible for enzyme synthesis when dietary cholesterol is high in animals: the same is observed for 3-hydroxy-3-methylglutaryl-CoA and the low density lipoprotein receptor.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB759Hu01 Recombinant Hydroxymethylglutaryl Coenzyme A Synthase (HMGCS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB759Hu01 Polyclonal Antibody to Hydroxymethylglutaryl Coenzyme A Synthase (HMGCS) WB; IHC
MAB759Hu22 Monoclonal Antibody to Hydroxymethylglutaryl Coenzyme A Synthase (HMGCS) WB; IHC; ICC; IP.
Assay Kits SEB759Hu ELISA Kit for Hydroxymethylglutaryl Coenzyme A Synthase (HMGCS) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB759Mu01 Recombinant Hydroxymethylglutaryl Coenzyme A Synthase (HMGCS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB759Mu01 Polyclonal Antibody to Hydroxymethylglutaryl Coenzyme A Synthase (HMGCS) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Hydroxymethylglutaryl Coenzyme A Synthase (HMGCS) CLIA Kit Customized Service Offer
n/a ELISA Kit for Hydroxymethylglutaryl Coenzyme A Synthase (HMGCS) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Hydroxymethylglutaryl Coenzyme A Synthase (HMGCS) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Hydroxymethylglutaryl Coenzyme A Synthase (HMGCS) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Hydroxymethylglutaryl Coenzyme A Synthase (HMGCS) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Hydroxymethylglutaryl Coenzyme A Synthase (HMGCS) CLIA Kit Customized Service Offer
n/a ELISA Kit for Hydroxymethylglutaryl Coenzyme A Synthase (HMGCS) ELISA Kit Customized Service Offer
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