Dihydropyrimidinase Like Protein 3 (DPYSL3)
[Edit]CRMP4; DRP3; ULIP; Dihydropyrimidinase-related protein 3; Collapsin response mediator protein 4; Unc-33-like phosphoprotein 1
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Byk et al. (1996) isolated and characterized a novel mouse phosphoprotein with significant homology to Unc33, a protein important for neuritic outgrowth and guidance in C. elegans. The cDNA isolated from mouse brain has an open reading frame that encodes a protein of 570 amino acids with a predicted molecular mass of 61,940 Da and a theoretical pI of 6.3. This sequence shows consensus sites for several protein kinases, corroborating biochemical studies indicating the phosphorylation of partially purified ULIP with protein kinase A (PKA), casein kinase-2 , and CDC2 kinase . ULIP was found to be cytoplasmic in PC12 cells, and it exclusively associated with neurons, particularly at neuromuscular junctions. Byk et al. (1996) stated that 3 human ESTs show between 76 and 96% overall identity to the mouse ULIP sequence.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB749Hu01 | Recombinant Dihydropyrimidinase Like Protein 3 (DPYSL3) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | n/a | Monoclonal Antibody to Dihydropyrimidinase Like Protein 3 (DPYSL3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Dihydropyrimidinase Like Protein 3 (DPYSL3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Dihydropyrimidinase Like Protein 3 (DPYSL3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Dihydropyrimidinase Like Protein 3 (DPYSL3) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB749Mu01 | Recombinant Dihydropyrimidinase Like Protein 3 (DPYSL3) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAB749Mu01 | Polyclonal Antibody to Dihydropyrimidinase Like Protein 3 (DPYSL3) | WB; IHC; ICC; IP. |
Assay Kits | n/a | CLIA Kit for Dihydropyrimidinase Like Protein 3 (DPYSL3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Dihydropyrimidinase Like Protein 3 (DPYSL3) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Dihydropyrimidinase Like Protein 3 (DPYSL3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Dihydropyrimidinase Like Protein 3 (DPYSL3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Dihydropyrimidinase Like Protein 3 (DPYSL3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Dihydropyrimidinase Like Protein 3 (DPYSL3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Dihydropyrimidinase Like Protein 3 (DPYSL3) | ELISA Kit Customized Service Offer |
- "A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution."Gene 180:157-163(1996) [PubMed] [Europe PMC] [Abstract]
- "Identification and characterization of a retinoic acid-regulated human homologue of the unc-33-like phosphoprotein gene (hUlip) from neuroblastoma cells."J. Biol. Chem. 272:12195-12201(1997) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and comparative analysis of human chromosome 5." Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
- , Submitted (DEC-2008) to UniProtKB
- "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
- "Distinct priming kinases contribute to differential regulation of collapsin response mediator proteins by glycogen synthase kinase-3 in vivo."J. Biol. Chem. 281:16591-16598(2006) [PubMed] [Europe PMC] [Abstract]
- "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
- "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
- "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]