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Angiotensin II Receptor 1 (AGTR1)

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AT1R; AG2S; AG2-S; AGTR1A; AGTR1B; AT1; AT1B; AT2R1; AT2-R1; AT2R1A; AT2R1B; HAT1R; AT1 Receptor; Angiotensin Receptor 1B

Angiotensin II Receptor 1 (AGTR1)
CCC B658
HGNC 336
MGI 87964
PubMed 17586781
RGD 2070
UniProt P30556
Wiki AGTR1

Angiotensin II receptor, type 1 or AT1 receptor is an angiotensin receptor. It has vasopressor effects and regulates aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system.It is the best elucidated angiotensin receptor.

The angiotensin receptor is activated by the vasoconstricting peptide angiotensin II. The activated receptor in turn couples to Gq/11 and thus activates phospholipase C and increases the cytosolic Ca2+ concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C. Activated receptor also inhibits adenylate cyclase and activates various tyrosine kinases.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB658Hu01 Recombinant Angiotensin II Receptor 1 (AGTR1) Positive Control; Immunogen; SDS-PAGE; WB.
RPB658Hu02 Recombinant Angiotensin II Receptor 1 (AGTR1) Positive Control; Immunogen; SDS-PAGE; WB.
RPB658Hu03 Recombinant Angiotensin II Receptor 1 (AGTR1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB658Hu01 Polyclonal Antibody to Angiotensin II Receptor 1 (AGTR1) WB; IHC; ICC; IP.
MAB658Hu22 Monoclonal Antibody to Angiotensin II Receptor 1 (AGTR1) WB; IHC; ICC; IP.
Assay Kits SEB658Hu ELISA Kit for Angiotensin II Receptor 1 (AGTR1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Angiotensin II Receptor 1 (AGTR1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Angiotensin II Receptor 1 (AGTR1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Angiotensin II Receptor 1 (AGTR1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Angiotensin II Receptor 1 (AGTR1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Angiotensin II Receptor 1 (AGTR1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB658Ra01 Recombinant Angiotensin II Receptor 1 (AGTR1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB658Ra01 Polyclonal Antibody to Angiotensin II Receptor 1 (AGTR1) WB; IHC; ICC; IP.
MAB658Ra21 Monoclonal Antibody to Angiotensin II Receptor 1 (AGTR1) WB; IHC; ICC; IP.
Assay Kits SEB658Ra ELISA Kit for Angiotensin II Receptor 1 (AGTR1) Enzyme-linked immunosorbent assay for Antigen Detection.
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  2. "Molecular cloning and sequencing of the gene encoding human angiotensin II type 1 receptor."Biochem. Biophys. Res. Commun. 183:8-13(1992) [PubMed] [Europe PMC] [Abstract]
  3. "Cloning and characterization of a human angiotensin II type 1 receptor."Biochem. Biophys. Res. Commun. 183:989-995(1992) [PubMed] [Europe PMC] [Abstract]
  4. "Molecular cloning, sequence analysis and expression of a cDNA encoding human type-1 angiotensin II receptor."Biochem. Biophys. Res. Commun. 183:910-916(1992) [PubMed] [Europe PMC] [Abstract]
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  10. "A strategy for precise and large scale identification of core fucosylated glycoproteins."Mol. Cell. Proteomics 8:913-923(2009) [PubMed] [Europe PMC] [Abstract]
  11. "Mutations in genes in the renin-angiotensin system are associated with autosomal recessive renal tubular dysgenesis."Nat. Genet. 37:964-968(2005) [PubMed] [Europe PMC] [Abstract]