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Solute Carrier Family 25 Member 20 (SLC25A20)

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CACT; CAC; Carnitine Acylcarnitine Translocase; Carnitine Acylcarnitine Carrier; Mitochondrial carnitine/acylcarnitine carrier protein

Solute Carrier Family 25 Member 20 (SLC25A20)
CCC B657
HGNC 1421
MGI 1928738
PubMed 15057979
RGD 621443
UniProt O43772
Wiki CACT

Carnitine-acylcarnitine translocase is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. This protein mediates the transport of acylcarnitines into mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway.

Mutations in this gene are associated with carnitine-acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB657Hu01 Recombinant Solute Carrier Family 25 Member 20 (SLC25A20) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB657Hu01 Polyclonal Antibody to Solute Carrier Family 25 Member 20 (SLC25A20) WB; IHC; ICC; IP.
MAB657Hu21 Monoclonal Antibody to Solute Carrier Family 25 Member 20 (SLC25A20) WB; IHC; ICC; IP.
Assay Kits SEB657Hu ELISA Kit for Solute Carrier Family 25 Member 20 (SLC25A20) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Solute Carrier Family 25 Member 20 (SLC25A20) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Solute Carrier Family 25 Member 20 (SLC25A20) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Solute Carrier Family 25 Member 20 (SLC25A20) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Solute Carrier Family 25 Member 20 (SLC25A20) CLIA Kit Customized Service Offer
n/a ELISA Kit for Solute Carrier Family 25 Member 20 (SLC25A20) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB657Ra01 Recombinant Solute Carrier Family 25 Member 20 (SLC25A20) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB657Ra01 Polyclonal Antibody to Solute Carrier Family 25 Member 20 (SLC25A20) WB; IHC; ICC; IP.
MAB657Ra21 Monoclonal Antibody to Solute Carrier Family 25 Member 20 (SLC25A20) WB; IHC; ICC; IP.
Assay Kits SEB657Ra ELISA Kit for Solute Carrier Family 25 Member 20 (SLC25A20) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "Cloning of the human carnitine-acylcarnitine carrier cDNA and identification of the molecular defect in a patient."Am. J. Hum. Genet. 61:1239-1245(1997) [PubMed] [Europe PMC] [Abstract]
  2. "The structure and organization of the human carnitine/acylcarnitine translocase (CACT) gene."Biochem. Biophys. Res. Commun. 252:770-774(1998) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  6. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  7. "A novel molecular defect of the carnitine acylcarnitine translocase gene in a Saudi patient."Clin. Genet. 64:163-165(2003) [PubMed] [Europe PMC] [Abstract]
  8. "Response to therapy in carnitine/acylcarnitine translocase (CACT) deficiency due to a novel missense mutation."Am. J. Med. Genet. A 126:150-155(2004) [PubMed] [Europe PMC] [Abstract]
  9. "Molecular and functional analysis of SLC25A20 mutations causing carnitine-acylcarnitine translocase deficiency."Hum. Mutat. 24:312-320(2004) [PubMed] [Europe PMC] [Abstract]