CD300 Antigen Like Family Member C (CD300c)

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IGSF16; CMRF35; LIR; CMRF-35A; CMRF35A; CMRF35-like molecule 6; Immunoglobulin Superfamily, Member 16

CD300 Antigen Like Family Member C (CD300c)

The CMRF35 antigen, which was identified by reactivity with a monoclonal antibody, is present on monocytes, neutrophils, and some T and B lymphocytes (Jackson et al., 1992).

The deduced 224-amino acid type I integral membrane protein contains a 20-residue N-terminal leader sequence, a single V-like Ig extracellular domain, 2 potential N-glycosylation sites, a potentially O-glycosylated hinge-like region, a hydrophobic transmembrane anchor that has a glutamate residue, and a short cytoplasmic tail of 19 amino acids. Northern blot analysis revealed expression of a 1.4-kb transcript in myeloid and B-lymphoid cell lines and in peripheral blood T cells. Expression was weak in other cell lines and undetectable in nonlymphoid tissues.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB654Hu01 Recombinant CD300 Antigen Like Family Member C (CD300c) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB654Hu01 Polyclonal Antibody to CD300 Antigen Like Family Member C (CD300c) WB; IHC
MAB654Hu21 Monoclonal Antibody to CD300 Antigen Like Family Member C (CD300c) WB; IHC; ICC; IP.
MAB654Hu22 Monoclonal Antibody to CD300 Antigen Like Family Member C (CD300c) WB; IHC; ICC; IP.
MAB654Hu23 Monoclonal Antibody to CD300 Antigen Like Family Member C (CD300c) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for CD300 Antigen Like Family Member C (CD300c) CLIA Kit Customized Service Offer
n/a ELISA Kit for CD300 Antigen Like Family Member C (CD300c) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant CD300 Antigen Like Family Member C (CD300c) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to CD300 Antigen Like Family Member C (CD300c) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to CD300 Antigen Like Family Member C (CD300c) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for CD300 Antigen Like Family Member C (CD300c) CLIA Kit Customized Service Offer
n/a ELISA Kit for CD300 Antigen Like Family Member C (CD300c) ELISA Kit Customized Service Offer
  1. "Molecular cloning of a novel member of the immunoglobulin gene superfamily homologous to the polymeric immunoglobulin receptor."Eur. J. Immunol. 22:1157-1163(1992) [PubMed] [Europe PMC] [Abstract]
  2. "The gene encoding the immunoregulatory signaling molecule CMRF-35A localized to human chromosome 17 in close proximity to other members of the CMRF-35 family."Tissue Antigens 57:415-423(2001) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Novel immunoglobulin superfamily gene cluster, mapping to a region of human chromosome 17q25, linked to psoriasis susceptibility."Hum. Genet. 112:34-41(2003) [PubMed] [Europe PMC] [Abstract]