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Transforming Growth Factor Beta Stimulated Protein Clone 22 (TSC22)

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TSC22D1; TGFB1I4; TSC22; hucep-2; Cerebral protein 2; Transforming Growth Factor Beta 1 Induced Transcript 4; TSC22 Domain Family,Member 1

Transforming Growth Factor Beta Stimulated Protein Clone 22 (TSC22)
CCC B637
HGNC 16826
MGI 109127
PubMed 10879745
UniProt Q15714
Wiki TSC22D1

domain family 1 is a member of a family of leucine zipper containing transcription factors with repressor activity and belongs to the large family of early response genes. TSC-22 regulates cell growth and differentiation, and cell death. Leucine zipper structure of TSC22 inhibits the anchorage independent growth of cancer cells.

TSC-22 is also an important downstream component of peroxisome proliferator-activated receptor (PPAR) and TGF-beta signaling during intestinal epithelial cell differentiation. TSC22 encodes a transcription factor and belongs to the large family of early response genes.TSC22D1 forms homodimers via its conserved leucine zipper domain and heterodimerizes with TSC22D4. TSC22D1 has transcriptional repressor activity.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB637Hu01 Recombinant Transforming Growth Factor Beta Stimulated Protein Clone 22 (TSC22) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB637Hu01 Polyclonal Antibody to Transforming Growth Factor Beta Stimulated Protein Clone 22 (TSC22) WB; IHC; ICC; IP.
MAB637Hu22 Monoclonal Antibody to Transforming Growth Factor Beta Stimulated Protein Clone 22 (TSC22) WB; IHC; ICC; IP.
Assay Kits SEB637Hu ELISA Kit for Transforming Growth Factor Beta Stimulated Protein Clone 22 (TSC22) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transforming Growth Factor Beta Stimulated Protein Clone 22 (TSC22) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transforming Growth Factor Beta Stimulated Protein Clone 22 (TSC22) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transforming Growth Factor Beta Stimulated Protein Clone 22 (TSC22) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transforming Growth Factor Beta Stimulated Protein Clone 22 (TSC22) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transforming Growth Factor Beta Stimulated Protein Clone 22 (TSC22) ELISA Kit Customized Service Offer
  1. "Cloning of the human homologue of the TGF beta-stimulated clone 22 gene."Biochem. Biophys. Res. Commun. 222:821-826(1996) [PubMed] [Europe PMC] [Abstract]
  2. "Molecular cloning and characterization of a transcription factor for the C-type natriuretic peptide gene promoter."Eur. J. Biochem. 242:460-466(1996) [PubMed] [Europe PMC] [Abstract]
  3. "The characteristics of different types of mRNA expressed in the human brain."Cyt. Genet. 30:41-47(1996) [PubMed] [Europe PMC] [Abstract]
  4. "Characterization of size-fractionated cDNA libraries generated by the in vitro recombination-assisted method."DNA Res. 9:47-57(2002) [PubMed] [Europe PMC] [Abstract]
  5. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  7. "The DNA sequence and analysis of human chromosome 13." Nature 428:522-528(2004) [PubMed] [Europe PMC] [Abstract]
  8. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  9. "Transforming growth factor-beta-stimulated clone-22 is a member of a family of leucine zipper proteins that can homo- and heterodimerize and has transcriptional repressor activity."J. Biol. Chem. 274:27439-27447(1999) [PubMed] [Europe PMC] [Abstract]
  10. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  11. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]