Fibromodulin (FMOD)
[Edit]SLRR2E; FM; Collagen-binding 59 kDa protein; Keratan sulfate proteoglycan fibromodulin; KSPG fibromodulin
-91494.jpg)
Fibromodulin is a member of a family of small interstitial proteoglycans that also includes decorin (DCN), biglycan (BGN), and lumican (LDC). The core proteins of these proteoglycans are structurally related, consisting of a central region composed of leucine-rich repeats flanked by disulfide-bonded terminal domains, with that for fibromodulin possessing up to 4 keratan sulfate chains within its leucine-rich domain.
Fibromodulin exhibits a wide tissue distribution, with the highest abundance observed in articular cartilage, tendon, and ligament. It has been suggested that fibromodulin participates in the assembly of the extracellular matrix by virtue of its ability to interact with type I and type II collagen fibrils and to inhibit fibrillogenesis in vitro.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB494Hu01 | Recombinant Fibromodulin (FMOD) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAB494Hu01 | Polyclonal Antibody to Fibromodulin (FMOD) | WB; IHC; ICC; IP. |
| MAB494Hu22 | Monoclonal Antibody to Fibromodulin (FMOD) | WB; IHC; ICC; IP. | |
| Assay Kits | SEB494Hu | ELISA Kit for Fibromodulin (FMOD) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Fibromodulin (FMOD) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Fibromodulin (FMOD) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Fibromodulin (FMOD) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Fibromodulin (FMOD) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Fibromodulin (FMOD) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB494Ra01 | Recombinant Fibromodulin (FMOD) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAB494Ra01 | Polyclonal Antibody to Fibromodulin (FMOD) | WB; IHC; ICC; IP. |
| MAB494Ra21 | Monoclonal Antibody to Fibromodulin (FMOD) | WB; IHC; ICC; IP. | |
| Assay Kits | SEB494Ra | ELISA Kit for Fibromodulin (FMOD) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Sus scrofa; Porcine (Pig)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Fibromodulin (FMOD) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Fibromodulin (FMOD) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Fibromodulin (FMOD) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Fibromodulin (FMOD) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Fibromodulin (FMOD) | ELISA Kit Customized Service Offer |
Organism species: Bos taurus; Bovine (Cattle)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Fibromodulin (FMOD) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Fibromodulin (FMOD) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Fibromodulin (FMOD) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Fibromodulin (FMOD) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Fibromodulin (FMOD) | ELISA Kit Customized Service Offer |
- "Structure and deduced amino acid sequence of the human fibromodulin gene."Biochim. Biophys. Acta 1174:204-206(1993) [PubMed] [Europe PMC] [Abstract]
- "Interaction of the small interstitial proteoglycans biglycan, decorin and fibromodulin with transforming growth factor beta."Biochem. J. 302:527-534(1994) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Identification of tyrosine sulfation in extracellular leucine-rich repeat proteins using mass spectrometry."J. Biol. Chem. 279:26-33(2004) [PubMed] [Europe PMC] [Abstract]
- "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]