Cluster Of Differentiation 99 (CD99)

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MIC2X; MIC2Y; MIC2; Antigen Identified By Monoclonal Antibodies 12E7,F21 And O13; E2 antigen; T-cell surface glycoprotein E2

Cluster Of Differentiation 99 (CD99)

CD99 is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma.

Cyclophilin A binds to CD99 and may act as a signaling regulator of CD99. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. Two transcript variants encoding different isoforms have been found for this gene.It is expressed on all leukocytes but highest on thymocytes and is believed to augment T-cell adhesion,apoptosis of double positive t cells,and participates in migration and activation.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB426Hu01 Recombinant Cluster Of Differentiation 99 (CD99) Positive Control; Immunogen; SDS-PAGE; WB.
EPB426Hu61 Eukaryotic Cluster Of Differentiation 99 (CD99) Positive Control; Immunogen; SDS-PAGE; WB.
RPB426Hu02 Recombinant Cluster Of Differentiation 99 (CD99) Positive Control; Immunogen; SDS-PAGE; WB.
RPB426Hu03 Recombinant Cluster Of Differentiation 99 (CD99) Positive Control; Immunogen; SDS-PAGE; WB.
APB426Hu61 Active Cluster Of Differentiation 99 (CD99) Cell culture; Activity Assays.
EPB426Hu63 Eukaryotic Cluster Of Differentiation 99 (CD99) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB426Hu01 Polyclonal Antibody to Cluster Of Differentiation 99 (CD99) WB; IHC; ICC; IP.
MAB426Hu22 Monoclonal Antibody to Cluster Of Differentiation 99 (CD99) WB; IHC; ICC; IP.
Assay Kits SEB426Hu ELISA Kit for Cluster Of Differentiation 99 (CD99) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB426Mu01 Recombinant Cluster Of Differentiation 99 (CD99) Positive Control; Immunogen; SDS-PAGE; WB.
RPB426Mu02 Recombinant Cluster Of Differentiation 99 (CD99) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB426Mu01 Polyclonal Antibody to Cluster Of Differentiation 99 (CD99) WB; IHC; ICC; IP; FCM
Assay Kits SEB426Mu ELISA Kit for Cluster Of Differentiation 99 (CD99) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB426Ra01 Recombinant Cluster Of Differentiation 99 (CD99) Positive Control; Immunogen; SDS-PAGE; WB.
RPB426Ra02 Recombinant Cluster Of Differentiation 99 (CD99) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB426Ra01 Polyclonal Antibody to Cluster Of Differentiation 99 (CD99) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Cluster Of Differentiation 99 (CD99) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cluster Of Differentiation 99 (CD99) ELISA Kit Customized Service Offer
  1. "The E2 antigen, a 32 kd glycoprotein involved in T-cell adhesion processes, is the MIC2 gene product."EMBO J. 8:3253-3259(1989) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Molecular genetics of MIC2: a gene shared by the human X and Y chromosomes."Cold Spring Harb. Symp. Quant. Biol. 51:205-212(1986) [PubMed] [Europe PMC] [Abstract]
  5. "Absence of methylation of a CpG-rich region at the 5' end of the MIC2 gene on the active X, the inactive X, and the Y chromosome."Proc. Natl. Acad. Sci. U.S.A. 85:5605-5609(1988) [PubMed] [Europe PMC] [Abstract]
  6. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  7. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]