![Small Nuclear Ribonucleoprotein Polypeptide C (SNRPC)](/upload/item/img/Small-Nuclear-Ribonucleoprotein-Polypeptide-C-(SNRPC)-91374.jpg)
The C polypeptide is one of the specific protein constituents of the U1 snRNP (small nuclear ribonucleoprotein) particle. See SNRPA. Patients with connective tissue diseases often produce autoantibodies against snRNP particles. By screening human expression libraries with anti-RNP sera, both Yamamoto et al. (1988) and Sillekens et al. (1988) isolated cDNAs encoding SNRPC.
Using Northern blot hybridization, Yamamoto et al. (1988) determined that SNRPC is expressed as an approximately 0.8-kb mRNA. Antibodies against SNRPC stained the nuclei of HeLa cells in a speckled pattern. Sillekens et al. (1988) reported that the predicted 159-amino acid SNRPC protein has an apparent molecular mass of 22 kD by SDS-PAGE.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB374Hu01 | Recombinant Small Nuclear Ribonucleoprotein Polypeptide C (SNRPC) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAB374Hu01 | Polyclonal Antibody to Small Nuclear Ribonucleoprotein Polypeptide C (SNRPC) | WB; IHC; ICC; IP. |
Assay Kits | n/a | CLIA Kit for Small Nuclear Ribonucleoprotein Polypeptide C (SNRPC) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Small Nuclear Ribonucleoprotein Polypeptide C (SNRPC) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Small Nuclear Ribonucleoprotein Polypeptide C (SNRPC) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Small Nuclear Ribonucleoprotein Polypeptide C (SNRPC) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Small Nuclear Ribonucleoprotein Polypeptide C (SNRPC) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Small Nuclear Ribonucleoprotein Polypeptide C (SNRPC) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Small Nuclear Ribonucleoprotein Polypeptide C (SNRPC) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Small Nuclear Ribonucleoprotein Polypeptide C (SNRPC) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Small Nuclear Ribonucleoprotein Polypeptide C (SNRPC) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Small Nuclear Ribonucleoprotein Polypeptide C (SNRPC) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Small Nuclear Ribonucleoprotein Polypeptide C (SNRPC) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Small Nuclear Ribonucleoprotein Polypeptide C (SNRPC) | ELISA Kit Customized Service Offer |
- "Human U1 snRNP-specific C protein: complete cDNA and protein sequence and identification of a multigene family in mammals."Nucleic Acids Res. 16:8307-8321(1988) [PubMed] [Europe PMC] [Abstract]
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- "Isolation and characterization of a complementary DNA expressing human U1 small nuclear ribonucleoprotein C polypeptide."J. Immunol. 140:311-317(1988) [PubMed] [Europe PMC] [Abstract]
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- "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
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- "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
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- "Crystal structure of human spliceosomal U1 snRNP at 5.5 A resolution."Nature 458:475-480(2009) [PubMed] [Europe PMC] [Abstract]