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Arginine Vasopressin Receptor 1A (AVPR1A)

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AVPR1; Antidiuretic Hormone Receptor 1A; SCCL Vasopressin Subtype 1a Receptor; V1-Vascular Vasopressin Receptor; Vascular/hepatic-type arginine vasopressin receptor

Arginine Vasopressin Receptor 1A (AVPR1A)
CCC B362
HGNC 895
MGI 1859216
PubMed 15098001
RGD 2185
UniProt P37288
Wiki AVPR1A

Arginine vasopressin receptor 1A (officially called AVPR1A) is one of the three major receptor types for arginine vasopressin (AVPR1B and AVPR2 being the others), and is present throughout the brain, as well as in the periphery in the liver, kidney, and vasculature.

Human AVPR1A cDNA is 1472 bp long and encodes a 418 amino-acid long polypeptide which shares 72%, 36%, 37%, and 45% sequence identity with rat Avpr1a, human AVPR2, rat Avpr2, and human oxytocin receptor (OXTR). AVPR1A is a G-protein coupled receptor (GPCR) with 7 transmembrane domains that couples to Gaq/11 GTP binding proteins, which along with Gbl, activate phospholipase C activity.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Arginine Vasopressin Receptor 1A (AVPR1A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Arginine Vasopressin Receptor 1A (AVPR1A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Arginine Vasopressin Receptor 1A (AVPR1A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Arginine Vasopressin Receptor 1A (AVPR1A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Arginine Vasopressin Receptor 1A (AVPR1A) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Arginine Vasopressin Receptor 1A (AVPR1A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Arginine Vasopressin Receptor 1A (AVPR1A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Arginine Vasopressin Receptor 1A (AVPR1A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Arginine Vasopressin Receptor 1A (AVPR1A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Arginine Vasopressin Receptor 1A (AVPR1A) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Arginine Vasopressin Receptor 1A (AVPR1A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Arginine Vasopressin Receptor 1A (AVPR1A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Arginine Vasopressin Receptor 1A (AVPR1A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Arginine Vasopressin Receptor 1A (AVPR1A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Arginine Vasopressin Receptor 1A (AVPR1A) ELISA Kit Customized Service Offer
  1. "Molecular cloning, sequencing, and functional expression of a cDNA encoding the human V1a vasopressin receptor."J. Biol. Chem. 269:3304-3310(1994) [PubMed] [Europe PMC] [Abstract]
  2. "Cloning, functional expression and tissue distribution of human cDNA for the vascular-type vasopressin receptor."Biochem. Biophys. Res. Commun. 203:72-79(1994) [PubMed] [Europe PMC] [Abstract]
  3. "Functional vasopressin V1 type receptors are present in variant as well as classical forms of small-cell carcinoma."Peptides 18:985-993(1997) [PubMed] [Europe PMC] [Abstract]
  4. "Expression of all known vasopressin receptor subtypes by small cell tumors implies a multifaceted role for this neuropeptide."Cancer Res. 58:1866-1871(1998) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Transmission disequilibrium testing of arginine vasopressin receptor 1A (AVPR1A) polymorphisms in autism."Mol. Psychiatry 7:503-507(2002) [PubMed] [Europe PMC] [Abstract]
  7. "A C-terminal segment of the V1R vasopressin receptor is unstructured in the crystal structure of its chimera with the maltose-binding protein."Acta Crystallogr. F 61:341-345(2005) [PubMed] [Europe PMC] [Abstract]