Neurofilament 3 (NEF3)
[Edit]NEFM; NF-M; NFM; Neurofilament,Medium Polypeptide; 160 kDa neurofilament protein; Neurofilament triplet M protein
Neurofilaments are the 10 nanometer (10nm) or intermediate filaments found specifically in neurons. The subunits of neurofilaments are related structurally to the 10nm or intermediate filaments of other tissues such as the keratin subunits, which make 10nm filaments expressed specifically in epithelia.
The class III intermediate filament protein subunit peripherin is found in neurofilaments along with the class IV subunits in a few neurons, mostly in the peripheral nervous system.
The International Radiation Hybrid Mapping Consortium mapped the NEF3 gene to chromosome 8p21 found that the mouse homologs of both of these genes appear to be on chromosome 14.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB326Hu01 | Recombinant Neurofilament 3 (NEF3) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPB326Hu02 | Recombinant Neurofilament 3 (NEF3) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAB326Hu01 | Polyclonal Antibody to Neurofilament 3 (NEF3) | WB; IHC; ICC; IP. |
MAB326Hu22 | Monoclonal Antibody to Neurofilament 3 (NEF3) | WB; IHC; ICC; IP. | |
PAB326Hu02 | Polyclonal Antibody to Neurofilament 3 (NEF3) | WB; IHC; ICC; IP. | |
Assay Kits | SEB326Hu | ELISA Kit for Neurofilament 3 (NEF3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Neurofilament 3 (NEF3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Neurofilament 3 (NEF3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Neurofilament 3 (NEF3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | SEB326Mu | ELISA Kit for Neurofilament 3 (NEF3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Neurofilament 3 (NEF3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Neurofilament 3 (NEF3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Neurofilament 3 (NEF3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Neurofilament 3 (NEF3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Neurofilament 3 (NEF3) | ELISA Kit Customized Service Offer |
- "The human mid-size neurofilament subunit: a repeated protein sequence and the relationship of its gene to the intermediate filament gene family."EMBO J. 6:1617-1626(1987) [PubMed] [Europe PMC] [Abstract]
- "Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs." Genome Res. 11:422-435(2001) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "DNA sequence and analysis of human chromosome 8." Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Identification of the major multiphosphorylation site in mammalian neurofilaments."Proc. Natl. Acad. Sci. U.S.A. 85:1998-2002(1988) [PubMed] [Europe PMC] [Abstract]