Gastrin (GT)
[Edit]GAST; GAS; Gastrin component I; Big gastrin; Gastrin component II; Gastrin component III
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Gastrin is a major physiological regulator of gastric acid secretion. It also has an important trophic or growth-promoting influence on the gastric mucosa. Gastrin is synthesized in G cells, which are located in gastric pits, primarily in the antrum region of the stomach and binds receptors found predominantly on parietal and enterochromaffin-like cells.In humans, gastrin is a hormone that stimulates secretion of gastric acid by the parietal cells of the stomach.
It is released by G cells in the stomach and duodenum.Gastrin is a linear peptide hormone produced by G cells of the duodenum and in the pyloric antrum of the stomach. In the Zollinger-Ellison syndrome, gastrin is produced at excessive levels, often by a gastrinoma of the antrum or the pancreas.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB224Hu01 | Recombinant Gastrin (GT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| SPB224Hu01 | Synthetic Gastrin (GT) | Immunogen; Blocking Peptide. | |
| SPB224Hu02 | Synthetic Gastrin (GT) | Immunogen; Blocking Peptide. | |
| CPB224Hu21 | OVA Conjugated Gastrin (GT) | Immunogen; SDS-PAGE; WB. | |
| CPB224Hu22 | OVA Conjugated Gastrin (GT) | Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAB224Hu01 | Polyclonal Antibody to Gastrin (GT) | WB; IHC; ICC; IP. |
| MAB224Hu22 | Monoclonal Antibody to Gastrin (GT) | WB; IHC; ICC; IP. | |
| LAB224Hu71 | Biotin-Linked Polyclonal Antibody to Gastrin (GT) | WB; IHC; ICC. | |
| LAB224Hu81 | FITC-Linked Polyclonal Antibody to Gastrin (GT) | WB; IHC; ICC; IF. | |
| PAB224Hu02 | Polyclonal Antibody to Gastrin (GT) | WB; IHC; ICC; IP. | |
| PAB224Hu03 | Polyclonal Antibody to Gastrin (GT) | WB; IHC; ICC; IP. | |
| MAB224Hu21 | Monoclonal Antibody to Gastrin (GT) | WB. | |
| MAB224Hu23 | Monoclonal Antibody to Gastrin (GT) | WB; IHC; ICC; IP. | |
| MAB224Hu24 | Monoclonal Antibody to Gastrin (GT) | WB; IHC; ICC; IP. | |
| MAB224Hu25 | Monoclonal Antibody to Gastrin (GT) | WB; IHC; ICC; IP. | |
| MAB224Hu26 | Monoclonal Antibody to Gastrin (GT) | WB; IHC; ICC; IP. | |
| Assay Kits | CEB224Hu | ELISA Kit for Gastrin (GT) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB224Mu01 | Recombinant Gastrin (GT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB224Mu02 | Recombinant Gastrin (GT) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAB224Mu01 | Polyclonal Antibody to Gastrin (GT) | WB; IHC; ICC; IP. |
| LAB224Mu81 | FITC-Linked Polyclonal Antibody to Gastrin (GT) | WB; IHC; ICC; IF. | |
| LAB224Mu71 | Biotin-Linked Polyclonal Antibody to Gastrin (GT) | WB; IHC; ICC. | |
| PAB224Mu02 | Polyclonal Antibody to Gastrin (GT) | WB; IHC; ICC; IP. | |
| Assay Kits | CEB224Mu | ELISA Kit for Gastrin (GT) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB224Ra01 | Recombinant Gastrin (GT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB224Ra02 | Recombinant Gastrin (GT) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAB224Ra01 | Polyclonal Antibody to Gastrin (GT) | WB; IHC; ICC; IP. |
| LAB224Ra81 | FITC-Linked Polyclonal Antibody to Gastrin (GT) | WB; IHC; ICC; IF. | |
| LAB224Ra71 | Biotin-Linked Polyclonal Antibody to Gastrin (GT) | WB; IHC; ICC. | |
| MAB224Ra21 | Monoclonal Antibody to Gastrin (GT) | WB; IHC; ICC; IP. | |
| PAB224Ra02 | Polyclonal Antibody to Gastrin (GT) | WB; IHC; ICC; IP. | |
| Assay Kits | CEB224Ra | ELISA Kit for Gastrin (GT) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SEB224Ra | ELISA Kit for Gastrin (GT) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Cavia (Guinea pig )
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB224Gu01 | Recombinant Gastrin (GT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAB224Gu01 | Polyclonal Antibody to Gastrin (GT) | WB; IHC; ICC; IP. |
| MAB224Gu21 | Monoclonal Antibody to Gastrin (GT) | WB; IHC; ICC; IP. | |
| Assay Kits | CEB224Gu | ELISA Kit for Gastrin (GT) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Canis familiaris; Canine (Dog)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB224Ca01 | Recombinant Gastrin (GT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB224Ca02 | Recombinant Gastrin (GT) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAB224Ca01 | Polyclonal Antibody to Gastrin (GT) | WB; IHC; ICC; IP. |
| MAB224Ca21 | Monoclonal Antibody to Gastrin (GT) | WB; IHC; ICC; IP. | |
| Assay Kits | CEB224Ca | ELISA Kit for Gastrin (GT) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Sus scrofa; Porcine (Pig)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Gastrin (GT) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Gastrin (GT) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Gastrin (GT) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Gastrin (GT) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Gastrin (GT) | ELISA Kit Customized Service Offer |
Organism species: Bos taurus; Bovine (Cattle)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Gastrin (GT) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Gastrin (GT) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Gastrin (GT) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Gastrin (GT) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Gastrin (GT) | ELISA Kit Customized Service Offer |
- "Expression of human gastrin gene in normal and gastrinoma tissues."Gene 50:345-352(1986) [PubMed] [Europe PMC] [Abstract]
- "Structural analysis of the gene encoding human gastrin: the large intron contains an Alu sequence."Proc. Natl. Acad. Sci. U.S.A. 81:4662-4666(1984) [PubMed] [Europe PMC] [Abstract]
- "Molecular cloning of the human gastrin gene."Nucleic Acids Res. 11:8197-8203(1983) [PubMed] [Europe PMC] [Abstract]
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- "Structure of a human gastrin gene."Proc. Natl. Acad. Sci. U.S.A. 81:1067-1069(1984) [PubMed] [Europe PMC] [Abstract]
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- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
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- "Aminoacid constitution of two gastrins isolated from Zollinger-Ellison tumour tissue."Gut 10:603-608(1969) [PubMed] [Europe PMC] [Abstract]
- "The human gastrin precursor. Characterization of phosphorylated forms and fragments."Biochem. J. 256:951-957(1988) [PubMed] [Europe PMC] [Abstract]
- "Post-poly(Glu) cleavage and degradation modified by O-sulfated tyrosine: a novel post-translational processing mechanism."EMBO J. 14:389-396(1995) [PubMed] [Europe PMC] [Abstract]
- "Tyrosine O-sulfation promotes proteolytic processing of progastrin."EMBO J. 14:3073-3079(1995) [PubMed] [Europe PMC] [Abstract]
- "Metabolism and acid secretory effect of sulfated and nonsulfated gastrin-6 in humans."Am. J. Physiol. 279:G903-G909(2000) [PubMed] [Europe PMC] [Abstract]