In man, metallothioneins are encoded by at least 10 to 12 genes separated into 2 groups designated MT-I and MT-II. Masters et al. (1994) noted that, unlike MT-I and MT-II, which are expressed in most organs, MT-III expression appears to be restricted to the brain, and MT-IV is only expressed in certain stratified squamous epithelia.
Class I metallothioneins contain 2 metal-binding domains: four divalent ions are chelated within cluster A of the alpha domain and are coordinated via cysteinyl thiolate bridges to 11 cysteine ligands. Cluster B, the corresponding region within the beta domain, can ligate three divalent ions to 9 cysteines.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB119Hu01 | Recombinant Metallothionein 1 (MT1) | Positive Control; Immunogen; SDS-PAGE; WB. |
EPB119Hu61 | Eukaryotic Metallothionein 1 (MT1) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAB119Hu01 | Polyclonal Antibody to Metallothionein 1 (MT1) | WB; IHC |
MAB119Hu22 | Monoclonal Antibody to Metallothionein 1 (MT1) | WB; IHC; ICC; IP. | |
Assay Kits | SEB119Hu | ELISA Kit for Metallothionein 1 (MT1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB119Mu01 | Recombinant Metallothionein 1 (MT1) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPB119Mu02 | Recombinant Metallothionein 1 (MT1) | Positive Control; Immunogen; SDS-PAGE; WB. | |
EPB119Mu61 | Eukaryotic Metallothionein 1 (MT1) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAB119Mu01 | Polyclonal Antibody to Metallothionein 1 (MT1) | WB; IHC; ICC; IP. |
PAB119Mu02 | Polyclonal Antibody to Metallothionein 1 (MT1) | WB; IHC; ICC; IP. | |
Assay Kits | SEB119Mu | ELISA Kit for Metallothionein 1 (MT1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB119Ra01 | Recombinant Metallothionein 1 (MT1) | Positive Control; Immunogen; SDS-PAGE; WB. |
NPB119Ra01 | Native Metallothionein 1 (MT1) | Positive Control; Immunogen; SDS-PAGE; WB. | |
RPB119Ra02 | Recombinant Metallothionein 1 (MT1) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAB119Ra01 | Polyclonal Antibody to Metallothionein 1 (MT1) | WB; IHC; ICC; IP. |
MAB119Ra21 | Monoclonal Antibody to Metallothionein 1 (MT1) | WB; IHC; ICC; IP. | |
PAB119Ra02 | Polyclonal Antibody to Metallothionein 1 (MT1) | WB; IHC; ICC; IP. | |
Assay Kits | SEB119Ra | ELISA Kit for Metallothionein 1 (MT1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Oryctolagus cuniculus (Rabbit)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Metallothionein 1 (MT1) | Recombinant Protein Customized Service Offer |
Antibodies | PAB119Rb52 | Polyclonal Antibody to Metallothionein 1 (MT1) | WB; IHC; ICC; IP. |
PAB119Rb51 | Polyclonal Antibody to Metallothionein 1 (MT1) | WB; IHC; ICC; IP. | |
LAB119Rb71 | Biotin-Linked Polyclonal Antibody to Metallothionein 1 (MT1) | WB; IHC; ICC. | |
Assay Kits | n/a | CLIA Kit for Metallothionein 1 (MT1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Metallothionein 1 (MT1) | ELISA Kit Customized Service Offer |
Organism species: Bos taurus; Bovine (Cattle)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Metallothionein 1 (MT1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Metallothionein 1 (MT1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Metallothionein 1 (MT1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Metallothionein 1 (MT1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Metallothionein 1 (MT1) | ELISA Kit Customized Service Offer |
Organism species: Chicken (Gallus)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB119Ga01 | Recombinant Metallothionein 1 (MT1) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAB119Ga01 | Polyclonal Antibody to Metallothionein 1 (MT1) | WB; IHC; ICC; IP. |
Assay Kits | n/a | CLIA Kit for Metallothionein 1 (MT1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Metallothionein 1 (MT1) | ELISA Kit Customized Service Offer |
- "Structural and functional analysis of the human metallothionein-IA gene: differential induction by metal ions and glucocorticoids."Cell 37:263-272(1984) [PubMed] [Europe PMC] [Abstract]
- "The sequence and analysis of duplication-rich human chromosome 16." Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]