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Cadherin, Fetal Kidney (KCAD)

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CDH6; Cadherin 6 Type 2; K-Cadherin

Cadherin, Fetal Kidney (KCAD)
CCC B096
HGNC 1765
MGI 107435
PubMed 9205085
RGD 2322
UniProt P55285
Wiki CDH6

Cadherin-6 is a type II classical cadherin from the cadherin superfamily. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail.

Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. Strong transcriptional expression of this gene has been observed in hepatocellular and renal carcinoma cell lines, suggesting a possible role in metastasis and invasion.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins EPB096Hu61 Eukaryotic Cadherin, Fetal Kidney (KCAD) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Cadherin, Fetal Kidney (KCAD) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cadherin, Fetal Kidney (KCAD) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cadherin, Fetal Kidney (KCAD) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cadherin, Fetal Kidney (KCAD) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cadherin, Fetal Kidney (KCAD) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cadherin, Fetal Kidney (KCAD) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cadherin, Fetal Kidney (KCAD) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cadherin, Fetal Kidney (KCAD) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cadherin, Fetal Kidney (KCAD) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cadherin, Fetal Kidney (KCAD) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cadherin, Fetal Kidney (KCAD) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cadherin, Fetal Kidney (KCAD) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cadherin, Fetal Kidney (KCAD) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cadherin, Fetal Kidney (KCAD) ELISA Kit Customized Service Offer
  1. "Isolation and sequence analysis of human cadherin-6 complementary DNA for the full coding sequence and its expression in human carcinoma cells."Cancer Res. 55:2206-2211(1995) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Diversity of the cadherin family: evidence for eight new cadherins in nervous tissue."Cell Regul. 2:261-270(1991) [PubMed] [Europe PMC] [Abstract]
  5. "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."J. Proteome Res. 4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
  6. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  7. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]