Chemerin (CHEM)

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TIG2; RARRES2; Tazarotene-Induced Gene 2; Retinoic Acid Receptor Responder 2,Tazarotene Induced; RAR-responsive protein TIG2

Chemerin (CHEM)

Chemerin is a novel protein identified as the natural ligand of ChemR23 (chemerinR), a previously orphan G protein-coupled receptor expressed in immature dendritic cells and macrophages. It is a member of the Cystatin superfamily. Chemerin is synthesized as a 163 aa secreted precursor, prochemerin, which contains a hydrophobic 20 aa N-terminal sequence, an intervening 137 aa Cystatin fold-containing domain, and a six aa C-terminal prosegment. It is activated by proteases of the coagulation, fibrinolytic, and inflammatory cascades and converted into a full agonist of chemerinR by proteolytic removal of the last six amino acids.Chemerin is a chemoattractant for cells bearing the Chem R23 receptor, including plasmacytoid dendritic cells and tissue macrophages.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA945Hu01 Recombinant Chemerin (CHEM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA945Hu01 Polyclonal Antibody to Chemerin (CHEM) IHC
MAA945Hu22 Monoclonal Antibody to Chemerin (CHEM) IHC
LAA945Hu54 APC-Linked Monoclonal Antibody to Chemerin (CHEM) IHC
MAA945Hu21 Monoclonal Antibody to Chemerin (CHEM) IHC
MAA945Hu23 Monoclonal Antibody to Chemerin (CHEM) IHC
Assay Kits SEA945Hu ELISA Kit for Chemerin (CHEM) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA945Mu01 Recombinant Chemerin (CHEM) Positive Control; Immunogen; SDS-PAGE; WB.
RPA945Mu02 Recombinant Chemerin (CHEM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA945Mu01 Polyclonal Antibody to Chemerin (CHEM) WB; IHC
PAA945Mu02 Polyclonal Antibody to Chemerin (CHEM) IHC
Assay Kits SEA945Mu ELISA Kit for Chemerin (CHEM) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA945Ra01 Recombinant Chemerin (CHEM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA945Ra01 Polyclonal Antibody to Chemerin (CHEM) IHC
LAA945Ra91 HRP-Linked Polyclonal Antibody to Chemerin (CHEM) IHC
MAA945Ra21 Monoclonal Antibody to Chemerin (CHEM) WB
MAA945Ra22 Monoclonal Antibody to Chemerin (CHEM) WB
MAA945Ra24 Monoclonal Antibody to Chemerin (CHEM) WB
MAA945Ra23 Monoclonal Antibody to Chemerin (CHEM) IHC
MAA945Ra25 Monoclonal Antibody to Chemerin (CHEM) IHC
Assay Kits SEA945Ra ELISA Kit for Chemerin (CHEM) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Chemerin (CHEM) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Chemerin (CHEM) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Chemerin (CHEM) Polyclonal Antibody Customized Service Offer
Assay Kits SEA945Po ELISA Kit for Chemerin (CHEM) Enzyme-linked immunosorbent assay for Antigen Detection.
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  15. "A novel adipocytokine, chemerin exerts anti-inflammatory roles in human vascular endothelial cells."Biochem. Biophys. Res. Commun. 423:152-157(2012) [PubMed] [Europe PMC] [Abstract]
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  18. "Chemerin is an antimicrobial agent in human epidermis."PLoS ONE 8:E58709-E58709(2013) [PubMed] [Europe PMC] [Abstract]