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Gamma-synuclein (SNCG)

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SNC-G; gSYN; SR; BCSG1; PERSYN; PRSN; Breast Cancer Specific Protein 1; Persyn; Synoretin; Synuclein Gamma

Gamma-synuclein (SNCG)
CCC A939
HGNC 11141
MGI 1298397
PubMed 11016747
RGD 70996
UniProt O76070
Wiki SNCG

Synuclein-gamma is a member of the synuclein family of proteins, which are believed to be involved in the pathogenesis of neurodegenerative diseases. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development. Gamma-synuclein is a synuclein protein found primarily in the peripheral nervous system (in primary sensory neurons, sympathetic neurons, and motor neurons) and retina. It is also detected in the brain, ovarian tumors, and in the olfactory epithelium. Gamma-synuclein is the least conserved of the synuclein proteins.Gamma-Synucleins expression in breast tumors is a marker for tumor progression as mammalian gamma-synuclein was first identified as breast cancer-specific gene 1 (BCSG1).

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA939Hu01 Recombinant Gamma-synuclein (SNCG) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA939Hu01 Polyclonal Antibody to Gamma-synuclein (SNCG) WB; IHC; ICC; IP.
MAA939Hu22 Monoclonal Antibody to Gamma-synuclein (SNCG) WB; IHC; ICC; IP.
Assay Kits SEA939Hu ELISA Kit for Gamma-synuclein (SNCG) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA939Mu01 Recombinant Gamma-synuclein (SNCG) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA939Mu01 Polyclonal Antibody to Gamma-synuclein (SNCG) WB; IHC; ICC; IP.
LAA939Mu71 Biotin-Linked Polyclonal Antibody to Gamma-synuclein (SNCG) WB; IHC; ICC.
Assay Kits n/a CLIA Kit for Gamma-synuclein (SNCG) CLIA Kit Customized Service Offer
n/a ELISA Kit for Gamma-synuclein (SNCG) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA939Ra01 Recombinant Gamma-synuclein (SNCG) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA939Ra01 Polyclonal Antibody to Gamma-synuclein (SNCG) WB; IHC; ICC; IP.
Assay Kits SEA939Ra ELISA Kit for Gamma-synuclein (SNCG) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "Identification of a breast cancer-specific gene, BCSG1, by direct differential cDNA sequencing."Cancer Res. 57:759-764(1997) [PubMed] [Europe PMC] [Abstract]
  2. "Organization, expression and polymorphism of the human persyn gene."Hum. Mol. Genet. 7:1417-1424(1998) [PubMed] [Europe PMC] [Abstract]
  3. "Identification, localization and characterization of the human gamma-synuclein gene."Hum. Genet. 103:106-112(1998) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
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  6. "Gamma synuclein: subcellular localization in neuronal and non-neuronal cells and effect on signal transduction."Cell Motil. Cytoskeleton 49:218-228(2001) [PubMed] [Europe PMC] [Abstract]
  7. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  8. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]