Heat Shock Protein 40 (HSP40)
[Edit]DnaJ; DNAJB1; Sis1; RSPH16B; HSPF1; DnaJ homolog subfamily B member 1; Radial Spoke 16 Homolog B; Heat Shock 40kDa Protein 1; DnaJ protein homolog 1
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Heat shock proteins or HSPs are being synthesized under different kind of stress conditions and act as molecular chaperones for protein molecules. Because these proteins were first found in cells that were exposed to high temperatures, they are called "heat shock proteins" and have been named according to their molecular weights.
Hsp40 (heat shock protein 40 kD) is a mammalian heat shock protein. Its prokaryotic homolog is DnaJ.Hsp40 is a family of heat-shock proteins that contain a 70 amino-acid consensus sequence known as the J domain. The J domain of Hsp40 interacts with Hsp70 heat shock proteins. Hsp40 heat-shock proteins play a role in regulating the ATPase activity of Hsp70 heat-shock proteins.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA872Hu01 | Recombinant Heat Shock Protein 40 (HSP40) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA872Hu01 | Polyclonal Antibody to Heat Shock Protein 40 (HSP40) | WB; IHC; ICC; IP. |
| MAA872Hu22 | Monoclonal Antibody to Heat Shock Protein 40 (HSP40) | WB; IHC; ICC; IP. | |
| LAA872Hu71 | Biotin-Linked Polyclonal Antibody to Heat Shock Protein 40 (HSP40) | WB; IHC; ICC. | |
| LAA872Hu81 | FITC-Linked Polyclonal Antibody to Heat Shock Protein 40 (HSP40) | WB; IHC; ICC; IF. | |
| Assay Kits | SEA872Hu | ELISA Kit for Heat Shock Protein 40 (HSP40) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA872Mu01 | Recombinant Heat Shock Protein 40 (HSP40) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA872Mu02 | Recombinant Heat Shock Protein 40 (HSP40) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAA872Mu01 | Polyclonal Antibody to Heat Shock Protein 40 (HSP40) | WB,IHC |
| PAA872Mu02 | Polyclonal Antibody to Heat Shock Protein 40 (HSP40) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA872Mu | ELISA Kit for Heat Shock Protein 40 (HSP40) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Heat Shock Protein 40 (HSP40) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Heat Shock Protein 40 (HSP40) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Heat Shock Protein 40 (HSP40) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Heat Shock Protein 40 (HSP40) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Heat Shock Protein 40 (HSP40) | ELISA Kit Customized Service Offer |
Organism species: Xenopus (Clawed frog)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Heat Shock Protein 40 (HSP40) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Heat Shock Protein 40 (HSP40) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Heat Shock Protein 40 (HSP40) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Heat Shock Protein 40 (HSP40) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Heat Shock Protein 40 (HSP40) | ELISA Kit Customized Service Offer |
- "A human homologue of the Escherichia coli DnaJ heat-shock protein."Nucleic Acids Res. 19:6645-6645(1991) [PubMed] [Europe PMC] [Abstract]
- "Cloning of a cDNA for heat-shock protein hsp40, a human homologue of bacterial DnaJ."Biochem. Biophys. Res. Commun. 197:235-240(1993) [PubMed] [Europe PMC] [Abstract]
- "Genomic cloning of a human heat shock protein 40 (Hsp40) gene (HSPF1) and its chromosomal localization to 19p13.2."Genomics 38:446-449(1996) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Intracellular localization and partial amino acid sequence of a stress-inducible 40-kDa protein in HeLa cells."Cell Struct. Funct. 17:77-86(1992) [PubMed] [Europe PMC] [Abstract]
- "The cellular inhibitor of the PKR protein kinase, P58(IPK), is an influenza virus-activated co-chaperone that modulates heat shock protein 70 activity."J. Biol. Chem. 274:3797-3803(1999) [PubMed] [Europe PMC] [Abstract]
- "Regulation of SR protein phosphorylation and alternative splicing by modulating kinetic interactions of SRPK1 with molecular chaperones."Genes Dev. 23:482-495(2009) [PubMed] [Europe PMC] [Abstract]
- "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
- "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
- "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
- "Nuclear magnetic resonance solution structure of the human Hsp40 (HDJ-1) J-domain."J. Mol. Biol. 260:224-235(1996) [PubMed] [Europe PMC] [Abstract]