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Apolipoprotein A2 (APOA2)

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Apo-A2; Apolipoprotein A-II; ProapoA-II; Truncated apolipoprotein A-II

Apolipoprotein A2 (APOA2)
CCC A604
HGNC 601
MGI 88050
PubMed 19901143
RGD 2131
UniProt P02652
Wiki APOA2

Apolipoprotein A-II is a protein , which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia.Apolipoprotein A-II, like apolipoprotein A-I (APOA1), is a major apolipoprotein in high density lipoprotein (HDL).

Apolipoprotein A-II is the second most abundant protein of high density lipoprotein particles. Warden et al. (1993) showed that in both mice and humans, the APOA2 gene is linked to a gene that controls plasma levels of apoA-II and that the APOA2 gene or its product influences, by an unknown mechanism, plasma levels of free fatty acids (FFA).

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA604Hu01 Recombinant Apolipoprotein A2 (APOA2) Positive Control; Immunogen; SDS-PAGE; WB.
EPA604Hu61 Eukaryotic Apolipoprotein A2 (APOA2) Positive Control; Immunogen; SDS-PAGE; WB.
RPA604Hu02 Recombinant Apolipoprotein A2 (APOA2) Positive Control; Immunogen; SDS-PAGE; WB.
APA604Hu61 Active Apolipoprotein A2 (APOA2) Cell culture; Activity Assays.
Antibodies PAA604Hu01 Polyclonal Antibody to Apolipoprotein A2 (APOA2) WB; IHC
MAA604Hu22 Monoclonal Antibody to Apolipoprotein A2 (APOA2) WB; IHC; ICC; IP.
LAA604Hu81 FITC-Linked Polyclonal Antibody to Apolipoprotein A2 (APOA2) WB; IHC; ICC; IF.
LAA604Hu71 Biotin-Linked Polyclonal Antibody to Apolipoprotein A2 (APOA2) WB; IHC; ICC.
Assay Kits SEA604Hu ELISA Kit for Apolipoprotein A2 (APOA2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA604Mu01 Recombinant Apolipoprotein A2 (APOA2) Positive Control; Immunogen; SDS-PAGE; WB.
RPA604Mu02 Recombinant Apolipoprotein A2 (APOA2) Positive Control; Immunogen; SDS-PAGE; WB.
EPA604Mu61 Eukaryotic Apolipoprotein A2 (APOA2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA604Mu01 Polyclonal Antibody to Apolipoprotein A2 (APOA2) WB; IHC; ICC; IP.
PAA604Mu02 Polyclonal Antibody to Apolipoprotein A2 (APOA2) WB; IHC; ICC; IP.
Assay Kits SEA604Mu ELISA Kit for Apolipoprotein A2 (APOA2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA604Ra01 Recombinant Apolipoprotein A2 (APOA2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA604Ra01 Polyclonal Antibody to Apolipoprotein A2 (APOA2) WB; IHC; ICC; IP.
MAA604Ra21 Monoclonal Antibody to Apolipoprotein A2 (APOA2) WB; IHC; ICC; IP.
Assay Kits SEA604Ra ELISA Kit for Apolipoprotein A2 (APOA2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rhesus monkey (Simian)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Apolipoprotein A2 (APOA2) Recombinant Protein Customized Service Offer
Antibodies PAA604Si01 Polyclonal Antibody to Apolipoprotein A2 (APOA2) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Apolipoprotein A2 (APOA2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Apolipoprotein A2 (APOA2) ELISA Kit Customized Service Offer

Organism species: Canis familiaris; Canine (Dog)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA604Ca01 Recombinant Apolipoprotein A2 (APOA2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Apolipoprotein A2 (APOA2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Apolipoprotein A2 (APOA2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Apolipoprotein A2 (APOA2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Apolipoprotein A2 (APOA2) ELISA Kit Customized Service Offer

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA604Po01 Recombinant Apolipoprotein A2 (APOA2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA604Po01 Polyclonal Antibody to Apolipoprotein A2 (APOA2) WB; IHC; ICC; IP.
LAA604Po81 FITC-Linked Polyclonal Antibody to Apolipoprotein A2 (APOA2) WB; IHC; ICC; IF.
LAA604Po71 Biotin-Linked Polyclonal Antibody to Apolipoprotein A2 (APOA2) WB; IHC; ICC.
MAA604Po21 Monoclonal Antibody to Apolipoprotein A2 (APOA2) WB; IHC; ICC; IP.
Assay Kits SEA604Po ELISA Kit for Apolipoprotein A2 (APOA2) Enzyme-linked immunosorbent assay for Antigen Detection.
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  2. "Human apolipoprotein A-II: nucleotide sequence of a cloned cDNA, and localization of its structural gene on human chromosome 1."Biochem. Biophys. Res. Commun. 123:1-7(1984) [PubMed] [Europe PMC] [Abstract]
  3. "Human apolipoproteins AI, AII, CII and CIII. cDNA sequences and mRNA abundance."Nucleic Acids Res. 12:3917-3932(1984) [PubMed] [Europe PMC] [Abstract]
  4. "The human apolipoprotein A-II gene: complete nucleic acid sequence and genomic organization."Nucleic Acids Res. 13:4597-4608(1985) [PubMed] [Europe PMC] [Abstract]
  5. "The human apolipoprotein AII gene: structural organization and sites of expression."Nucleic Acids Res. 13:6387-6398(1985) [PubMed] [Europe PMC] [Abstract]
  6. "Molecular cloning and sequence analysis of human apolipoprotein A-II cDNA."Methods Enzymol. 128:745-752(1986) [PubMed] [Europe PMC] [Abstract]
  7. "Sequence polymorphism at the human apolipoprotein AII gene (APOA2): unexpected deficit of variation in an African-American sample."Hum. Genet. 111:75-87(2002) [PubMed] [Europe PMC] [Abstract]
  8. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  9. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  10. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  11. "Isolation and characterization of the tryptic and cyanogen bromide peptides of apoLp-Gln-II (apoA-II), plasma high density apolipoprotein."J. Biol. Chem. 247:7519-7527(1972) [PubMed] [Europe PMC] [Abstract]
  12. "Cell-free translation of human liver apolipoprotein AI and AII mRNA. Processing of primary translation products."Hoppe-Seyler's Z. Physiol. Chem. 364:227-237(1983) [PubMed] [Europe PMC] [Abstract]
  13. "A splice-junction mutation responsible for familial apolipoprotein A-II deficiency."Am. J. Hum. Genet. 46:822-827(1990) [PubMed] [Europe PMC] [Abstract]
  14. "Structure of human apolipoprotein D: locations of the intermolecular and intramolecular disulfide links."Biochemistry 33:12451-12455(1994) [PubMed] [Europe PMC] [Abstract]
  15. "Cloning and characterization of a novel apolipoprotein A-I-binding protein, AI-BP, secreted by cells of the kidney proximal tubules in response to HDL or ApoA-I."Genomics 79:693-702(2002) [PubMed] [Europe PMC] [Abstract]
  16. "Characterization of specifically oxidized apolipoproteins in mildly oxidized high density lipoprotein."J. Lipid Res. 44:349-355(2003) [PubMed] [Europe PMC] [Abstract]
  17. "Novel mass spectrometric immunoassays for the rapid structural characterization of plasma apolipoproteins."J. Lipid Res. 44:630-639(2003) [PubMed] [Europe PMC] [Abstract]
  18. "NDRG1 interacts with APO A-I and A-II and is a functional candidate for the HDL-C QTL on 8q24."Biochem. Biophys. Res. Commun. 332:982-992(2005) [PubMed] [Europe PMC] [Abstract]
  19. "An initial characterization of the serum phosphoproteome."J. Proteome Res. 8:5523-5531(2009) [PubMed] [Europe PMC] [Abstract]
  20. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  21. "LC-MS/MS characterization of O-glycosylation sites and glycan structures of human cerebrospinal fluid glycoproteins."J. Proteome Res. 12:573-584(2013) [PubMed] [Europe PMC] [Abstract]
  22. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  23. "Structures of apolipoprotein A-II and a lipid-surrogate complex provide insights into apolipoprotein-lipid interactions."Biochemistry 41:11681-11691(2002) [PubMed] [Europe PMC] [Abstract]