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Aquaporin 3, Gill Blood Group (AQP3)

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GIL; Aquaglyceroporin-3

Aquaporin 3, Gill Blood Group (AQP3)
CCC A581
HGNC 636
MGI 1333777
PubMed 9124401
RGD 68428
UniProt Q92482
Wiki Aquaporin_3

Aquaporin 3 is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 3 is localized at the basal lateral membranes of collecting duct cells in the kidney. In addition to its water channel function, aquaporin 3 has been found to facilitate the transport of nonionic small solutes such as urea and glycerol, but to a smaller degree. 

Aquaporin 3 is found in the basolateral cell membrane of principal collecting duct cells and provide a pathway for water to exit these cells. In kidney, AQP3 gene expression is not regulated by vasopressin (ADH). This protein is also a determinant for the GIL blood group system.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA581Hu01 Recombinant Aquaporin 3, Gill Blood Group (AQP3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAA581Hu22 Monoclonal Antibody to Aquaporin 3, Gill Blood Group (AQP3) WB; IHC; ICC; IP.
Assay Kits SEA581Hu ELISA Kit for Aquaporin 3, Gill Blood Group (AQP3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA581Mu01 Recombinant Aquaporin 3, Gill Blood Group (AQP3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA581Mu01 Polyclonal Antibody to Aquaporin 3, Gill Blood Group (AQP3) WB; IHC; ICC; IP.
Assay Kits SEA581Mu ELISA Kit for Aquaporin 3, Gill Blood Group (AQP3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Aquaporin 3, Gill Blood Group (AQP3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Aquaporin 3, Gill Blood Group (AQP3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Aquaporin 3, Gill Blood Group (AQP3) Polyclonal Antibody Customized Service Offer
Assay Kits SEA581Ra ELISA Kit for Aquaporin 3, Gill Blood Group (AQP3) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "Structure and chromosomal localization of a human water channel (AQP3) gene."Genomics 27:352-354(1995) [PubMed] [Europe PMC] [Abstract]
  2. "AQP3 deficiency in humans and the molecular basis of a novel blood group system, GIL."J. Biol. Chem. 277:45854-45859(2002) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "DNA sequence and analysis of human chromosome 9." Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Regulation of aquaporin 3 expression by magnesium ion."Eur. J. Pharmacol. 588:26-32(2008) [PubMed] [Europe PMC] [Abstract]