Interferon Gamma Induced Protein 10kDa (IP10)
[Edit]CXCL10; C7; IFI10; INP10; SCYB10; Crg2; GIP10; Mob1; Chemokine C-X-C Motif Ligand 10; Small Inducible Cytokine Subfamily B(Cys-X-Cys)Member 10
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Chemokine (C-X-C motif) ligand 10 (CXCL10) or IP-10 is a small cytokine belonging to the CXC chemokine family that is also known as 10 kDa interferon-gamma-induced protein (γ-IP10 or IP-10). CXCL10 is secreted by several cell types in response to IFN-γ. These cell types include monocytes, endothelial cells and fibroblasts.
CXCL10 has been attributed to several roles, such as chemoattraction for monocytes/macrophages, T cells, NK cells, and dendritic cells, promotion of T cell adhesion to endothelial cells, antitumor activity, and inhibition of bone marrow colony formation and angiogenesis. The gene for CXCL10 is located on human chromosome 4 in a cluster among several other CXC chemokines.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA371Mu01 | Recombinant Interferon Gamma Induced Protein 10kDa (IP10) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA371Mu02 | Recombinant Interferon Gamma Induced Protein 10kDa (IP10) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAA371Mu01 | Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) | WB; IHC; ICC; IP. |
| LAA371Mu71 | Biotin-Linked Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) | WB; IHC; ICC. | |
| LAA371Mu81 | FITC-Linked Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) | WB; IHC; ICC; IF. | |
| PAA371Mu02 | Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA371Mu | ELISA Kit for Interferon Gamma Induced Protein 10kDa (IP10) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA371Ra01 | Recombinant Interferon Gamma Induced Protein 10kDa (IP10) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA371Ra01 | Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) | WB; IHC; ICC; IP. |
| MAA371Ra21 | Monoclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA371Ra | ELISA Kit for Interferon Gamma Induced Protein 10kDa (IP10) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Hamster (Chinese hamster)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA371Ha01 | Recombinant Interferon Gamma Induced Protein 10kDa (IP10) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | n/a | Monoclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Interferon Gamma Induced Protein 10kDa (IP10) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Interferon Gamma Induced Protein 10kDa (IP10) | ELISA Kit Customized Service Offer |
Organism species: Canis familiaris; Canine (Dog)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA371Ca01 | Recombinant Interferon Gamma Induced Protein 10kDa (IP10) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA371Ca01 | Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) | WB; IHC; ICC; IP. |
| LAA371Ca71 | Biotin-Linked Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) | WB; IHC; ICC. | |
| MAA371Ca21 | Monoclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA371Ca | ELISA Kit for Interferon Gamma Induced Protein 10kDa (IP10) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Bos taurus; Bovine (Cattle)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA371Bo01 | Recombinant Interferon Gamma Induced Protein 10kDa (IP10) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA371Bo01 | Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) | WB; IHC; ICC; IP. |
| MAA371Bo21 | Monoclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA371Bo | ELISA Kit for Interferon Gamma Induced Protein 10kDa (IP10) | Enzyme-linked immunosorbent assay for Antigen Detection. |
- "Gamma-interferon transcriptionally regulates an early-response gene containing homology to platelet proteins."Nature 315:672-676(1985) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
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- "Citrullination of CXCL10 and CXCL11 by peptidylarginine deiminase: a naturally occurring posttranslational modification of chemokines and new dimension of immunoregulation."Blood 112:2648-2656(2008) [PubMed] [Europe PMC] [Abstract]
- "The CXCR3 binding chemokine IP-10/CXCL10: structure and receptor interactions."Biochemistry 41:10418-10425(2002) [PubMed] [Europe PMC] [Abstract]